MECP2
methyl CpG binding protein 2 (Rett syndrome)
Synonimy:
AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT
Gatunek:
Human MECP2 (4204), Mouse Mecp2 (17257), Rat Mecp2 (29386), domestic cat MECP2 (101082385), Zebrafish mecp2 (335250), Domestic Rabbit MECP2 (100328751), dog MECP2 (612973), domestic guinea pig Mecp2 (100734864), sheep MECP2 (101121154), naked mole-rat Mecp2 (101700584)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(4204) Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009]
- Mouse(17257) methyl CpG binding protein 2
- Rat(29386) methyl CpG binding protein 2
- domestic cat(101082385) methyl CpG binding protein 2 (Rett syndrome)
- Zebrafish(335250) methyl CpG binding protein 2
- Domestic Rabbit(100328751) methyl CpG binding protein 2 (Rett syndrome)
- dog(612973) methyl CpG binding protein 2 (Rett syndrome)
- domestic guinea pig(100734864) methyl CpG binding protein 2 (Rett syndrome)
- sheep(101121154) methyl CpG binding protein 2 (Rett syndrome)
- naked mole-rat(101700584) methyl CpG binding protein 2 (Rett syndrome)
- cow(539629) methyl CpG binding protein 2 (Rett syndrome)
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MeCP2 Antibody, clone 4H7, clone 4H7, from rat,
Reaktywność gatunkowa
mouse, porcine, rat
Zastosowanie
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-MECP2 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-MECP2 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoclonal Anti-MECP2 antibody produced in mouse, clone 4B6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-MECP2 antibody produced in mouse, clone 1B11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Numer produktu
Opis
Gatunek