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ITGAV

integrin, alpha V

Synonimy:
CD51, MSK8, VNRA, VTNR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Integrin αVβ5 Antibody, clone P1F6, FITC conjugated, clone P1F6, Chemicon®, from mouse,
Reaktywność gatunkowa
chicken, human
Zastosowanie
flow cytometry
immunofluorescence

immunohistochemistry
Anti-Integrin αVβ3 Antibody, clone LM609, FITC conjugated, clone LM609, Chemicon®, from mouse,
Reaktywność gatunkowa
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Zastosowanie
flow cytometry
immunohistochemistry
Milli-Mark® Przeciwciało anty-Integryna αVβ3, klon LM609-FITC, clone LM609, Milli-Mark®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Anti-Integrin αVβ5 Antibody, clone 15F11, Azide Free, clone 15F11, Chemicon®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
flow cytometry

immunocytochemistry

immunoprecipitation (IP)
Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6), liquid, clone 272-17E6, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie

Proteins

Numer produktu
Opis
Gatunek
Ludzkie białko integryny αVβ3, formulacja Triton X-100, ,
Gatunek
human
Human Integrin αVβ3, Octyl-β-D-glucopyranoside Formulation, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Itgav,
Gatunek
mouse
MISSION® esiRNA, targeting human ITGAV,
Gatunek
human