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Merck

ITGA2B

integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Synonimy:
BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3674) Summary: ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008]
  • Mouse(16399) integrin alpha 2b
  • Rat(685269) integrin, alpha 2B
  • domestic guinea pig(100727374) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • naked mole-rat(101714332) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Horse(100009697) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • cow(515011) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • sheep(101115719) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Zebrafish(445380) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)
  • domestic cat(101100930) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • dog(403789) integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

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Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Gatunek
human
Acetylsalicylic acid, analytical standard,
Gatunek
human
Arg-Gly-Asp-Ser, ≥95% (HPLC),
Gatunek
mouse, human
Aspirin, meets USP testing specifications,
Gatunek
human
Acetylsalicylic acid, ≥99.0%,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Milli-Mark® Anti-CD41-FITC Antibody, clone 5B12, clone 5B12, Milli-Mark®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Anti-ITGA2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoclonal Anti-CD41a antibody produced in mouse, clone HIP8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, nonhuman primates
Zastosowanie
flow cytometry
Monoclonal Anti-CD41 antibody produced in mouse, clone MEM-06, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Anti-ITGA2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Tirofiban, ≥98.5% (HPLC),
Gatunek
human
Tirofiban hydrochloride monohydrate, ≥98% (HPLC),
Gatunek
human
Acetylsalicylic acid, analytical standard,
Gatunek
human
Aspirin, meets USP testing specifications,
Gatunek
human
Acetylsalicylic acid, ≥99.0%,
Gatunek
human