FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Synonimy:
CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3
Gatunek:
Human FCGR3A (2214), Rat Fcgr3a (304966), dog FCGR3A (478984), sheep FCGR3A (100192433), cow FCGR3A (281766)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2214) Summary: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Rat(304966) Fc fragment of IgG, low affinity IIIa, receptor
- dog(478984) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- sheep(100192433) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
- cow(281766) Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CD16-FITC antibody produced in mouse, clone LNK16, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, nonhuman primates
Zastosowanie
flow cytometry
Monoclonal Anti-CD16 antibody produced in mouse, clone MEM-154, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Monoclonal Anti-CD16-FITC antibody produced in mouse, clone MEM-154, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
Monoclonal Anti-CD16 antibody produced in mouse, clone LNK16, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, nonhuman primates
Zastosowanie
flow cytometry
Monoclonal Anti-FCGR3A, (C-terminal) antibody produced in mouse, clone 2B11, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
esiRNA
Numer produktu
Opis
Gatunek