E2F1
E2F transcription factor 1
Synonimy:
E2F-1, RBAP1, RBBP3, RBP3
Gatunek:
Human E2F1 (1869), Mouse E2f1 (13555), Rat E2f1 (399489), chicken E2F1 (396142), Thale Cress E2F1 (832283), naked mole-rat E2f1 (101717980), Horse E2F1 (100069192), cow E2F1 (535369), sheep E2F1 (101117526), dog E2F1 (485839) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1869) Summary: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(13555) E2F transcription factor 1
- Rat(399489) E2F transcription factor 1
- chicken(396142) E2F transcription factor 1
- Thale Cress(832283) E2F transcription factor 1
- naked mole-rat(101717980) E2F transcription factor 1
- Horse(100069192) E2F transcription factor 1
- cow(535369) E2F transcription factor 1
- sheep(101117526) E2F transcription factor 1
- dog(485839) E2F transcription factor 1
- domestic guinea pig(100729531) E2F transcription factor 1
- domestic cat(101098454) E2F transcription factor 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-E2F1, klon 5Z5U3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Przeciwciało anty-E2F-1, klony KH20 i KH95, Upstate®, from mouse,
Reaktywność gatunkowa
xenopus, human
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-E2F1 antibody produced in mouse, clone 2E10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
western blot
proximity ligation assay
western blot
Anti-E2F1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
western blot
Anti-E2F1, (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
western blot
Proteins
Numer produktu
Opis
Gatunek