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Merck

CYP11A1

cytochrome P450, family 11, subfamily A, polypeptide 1

Synonimy:
CYP11A, CYPXIA1, P450SCC
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1583) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
  • Mouse(13070) cytochrome P450, family 11, subfamily a, polypeptide 1
  • Rat(29680) cytochrome P450, family 11, subfamily a, polypeptide 1
  • sheep(100048994) cytochrome P450, family 11, subfamily A, polypeptide 1
  • Domestic Rabbit(100345737) cytochrome P450, family 11, subfamily A, polypeptide 1
  • cow(338048) cytochrome P450, family 11, subfamily A, polypeptide 1
  • Zebrafish(80374) cytochrome P450, subfamily XIA, polypeptide 1
  • chicken(414838) cytochrome P450, family 11, subfamily A, polypeptide 1
  • Horse(100034229) cytochrome P450 cholesterol side-chain cleavage
  • dog(478365) cytochrome P450, family 11, subfamily A, polypeptide 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CYP11A1 Antibody, clone 2M5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
chimpanzee, human
Zastosowanie
affinity binding assay
immunofluorescence

immunohistochemistry

western blot
Anti-CYP11A1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-CYP11A1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-Cytochrome P450 (scc) Antibody, a.a. 509-526, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
2,4′-DDD, PESTANAL®, analytical standard,
Gatunek
human
Mitotane, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
DL-Aminoglutethimide, ,
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CYP11A1,
Gatunek
human
MISSION® esiRNA, targeting mouse Cyp11a1,
Gatunek
mouse