CDK6
cyclin-dependent kinase 6
Synonimy:
PLSTIRE
Gatunek:
Human CDK6 (1021), Mouse Cdk6 (12571), Rat Cdk6 (114483), domestic guinea pig Cdk6 (100732773), naked mole-rat Cdk6 (101719908), Domestic Rabbit CDK6 (100009040), sheep CDK6 (100144761), Horse CDK6 (100061625), cow CDK6 (511754), dog CDK6 (609920) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1021) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]
- Mouse(12571) cyclin-dependent kinase 6
- Rat(114483) cyclin-dependent kinase 6
- domestic guinea pig(100732773) cyclin-dependent kinase 6
- naked mole-rat(101719908) cyclin-dependent kinase 6
- Domestic Rabbit(100009040) cyclin-dependent kinase 6
- sheep(100144761) cyclin-dependent kinase 6
- Horse(100061625) cyclin-dependent kinase 6
- cow(511754) cyclin-dependent kinase 6
- dog(609920) cyclin-dependent kinase 6
- domestic cat(100037415) cyclin-dependent kinase 6
- chicken(420558) cyclin-dependent kinase 6
- Zebrafish(100034507) cyclin-dependent kinase 6
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-CDK6 (pTyr13) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CDK6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-CDK6 antibody produced in mouse, clone 8H4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
immunofluorescence
immunohistochemistry
proximity ligation assay
western blot
Anti-CDK6 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-CDK6 (Ab-24) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
Proteins
Numer produktu
Opis
Gatunek
Cdk6/Cyclin D3 Protein, active, 10 µg, Active, N-terminal, His6-tagged full length human Cdk6 complexed with N-terminal GST-tagged full-length human Cyclin D3, for use in Kinase Assays.,
Gatunek
human
CDK6/CyclinD1, active, His/GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human