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Merck

CASP7

caspase 7, apoptosis-related cysteine peptidase

Synonimy:
CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(840) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  • Mouse(12369) caspase 7
  • Rat(64026) caspase 7
  • Goat(100861343) caspase 7, apoptosis-related cysteine peptidase
  • dog(486896) caspase 7, apoptosis-related cysteine peptidase
  • Zebrafish(553634) caspase 7, apoptosis-related cysteine peptidase
  • chicken(423901) caspase 7, apoptosis-related cysteine peptidase
  • naked mole-rat(101709568) caspase 7, apoptosis-related cysteine peptidase
  • domestic guinea pig(100715159) caspase 7, apoptosis-related cysteine peptidase
  • cow(526279) caspase 7, apoptosis-related cysteine peptidase
  • sheep(101122741) caspase 7, apoptosis-related cysteine peptidase
  • domestic cat(768262) caspase 7, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Ludzka kaspaza-7 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Caspase-7 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-Caspase-7 Antibody, clone 1E21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry

western blot
Monoclonal Anti-Caspase 7 antibody produced in rat, clone 11E4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunoprecipitation (IP)
microarray

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
N-Acetyl-Asp-Glu-Val-Asp-al, ≥95%, powder,
Gatunek
human
NSCI, ≥97% (HPLC), solid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CASP7,
Gatunek
human