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Merck

CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

Synonimy:
CACNA1HB, Cav3.2, ECA6, EIG6
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8912) Summary: This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
  • Mouse(58226) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • Rat(114862) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • dog(403533) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic cat(101090071) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • domestic guinea pig(100720102) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • naked mole-rat(101712631) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • chicken(416526) calcium channel, voltage-dependent, T type, alpha 1H subunit
  • cow(282412) calcium channel, voltage-dependent, T type, alpha 1H subunit

Custom & Knockdown Gene Products

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Gabapentin solution, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CACNA1H antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Anti-CACNA1H antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Anti-Calcium Channel CaV3.2 (α1H) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
Przeciwciało anty-Cav3.2, Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Ethosuximide, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Ethosuximide, ,
Gatunek
human
Ethosuximide, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Trimethadione, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Ethosuximide, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human