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Merck

BCL2L1

BCL2-like 1

Synonimy:
BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(598) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
  • Mouse(12048) BCL2-like 1
  • Rat(24888) Bcl2-like 1
  • Domestic Rabbit(100008875) BCL2-like 1
  • domestic guinea pig(100730495) BCL2-like 1
  • Zebrafish(114401) bcl2-like 1
  • cow(282152) BCL2-like 1
  • domestic cat(493701) BCL2-like 1
  • chicken(373954) BCL2-like 1
  • dog(403618) BCL2-like 1
  • sheep(443061) BCL2-like 1
  • naked mole-rat(101713410) BCL2-like 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-BCL2L1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
canine, human
Zastosowanie
western blot
Anti-BCL2L1 antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, horse, human, pig, rabbit, sheep
Zastosowanie
western blot
Przeciwciało anty-Bcl-XL, klon 2V10G9, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Przeciwciało anty-Bcl-X, klon 2H12, clone 2H12, Chemicon®, from mouse,
Reaktywność gatunkowa
human, mouse, pig, rat
Zastosowanie
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-Bcl-xL Antibody, clone 1O8 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
bovine, canine, feline, human, monkey, mouse, porcine, rat
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

western blot

Proteins

Numer produktu
Opis
Gatunek
Bcl-xL Active human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human BCL2L1,
Gatunek
human
MISSION® esiRNA, targeting mouse Bcl2l1,
Gatunek
mouse