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AANAT

aralkylamine N-acetyltransferase

Synonimy:
DSPS, SNAT
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(15) Summary: The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(11298) arylalkylamine N-acetyltransferase
  • Rat(25120) aralkylamine N-acetyltransferase
  • chicken(396066) aralkylamine N-acetyltransferase
  • sheep(443531) aralkylamine N-acetyltransferase
  • domestic guinea pig(100724241) aralkylamine N-acetyltransferase
  • domestic cat(101098178) aralkylamine N-acetyltransferase
  • dog(483331) aralkylamine N-acetyltransferase
  • Goat(100860947) aralkylamine N-acetyltransferase
  • cow(281583) arylalkylamine N-acetyltransferase
  • naked mole-rat(101713893) aralkylamine N-acetyltransferase

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-Serotonin N-Acetyltransferase (N-Terminal) (pThr29) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
ANTI-AANAT (N-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-AANAT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-AANAT Antibody, serum, Chemicon®,
Reaktywność gatunkowa
bovine, fish, human, rat, sheep
Zastosowanie
western blot
Anti-Serotonin N-Acetyltransferase (C-Terminal) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
western blot