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A3903

Sigma-Aldrich

1-Aminocyclopropanecarboxylic acid

≥98% (TLC), powder, NMDA agonist

Sinónimos:

ACC, ACPC

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100 MG
MXP 3,286.00
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MXP 5,410.00
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MXP 17,531.00

MXP 3,286.00

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100 MG
MXP 3,286.00
250 MG
MXP 5,410.00
1 G
MXP 17,531.00

About This Item

Fórmula empírica (notación de Hill):
C4H7NO2
Número de CAS:
22059-21-8
Peso molecular:
101.10
Beilstein/REAXYS Number:
2076413
MDL number:
MFCD00009944
UNSPSC Code:
12352209
PubChem Substance ID:
24890826
NACRES:
NA.32

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Nombre del producto

1-Aminocyclopropanecarboxylic acid, ≥98% (TLC), powder

Quality Level

200

assay

≥98% (TLC)

form

powder

storage condition

(Keep container tightly closed in a dry and well-ventilated place.
Keep in a dry place.)

color

white

mp

229-231 °C (lit.)

solubility

water: 49.00-51.00 mg/mL, clear, colorless

SMILES string

NC1(CC1)C(O)=O

InChI

1S/C4H7NO2/c5-4(1-2-4)3(6)7/h1-2,5H2,(H,6,7)

InChI key

PAJPWUMXBYXFCZ-UHFFFAOYSA-N

Gene Information

human ... NARG2(79664)
mouse ... NARG2(93697)
rat ... LOC686240(686240) , NARG2(691379)

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General description

Research area: Cell Signaling

1-Aminocyclopropanecarboxylic acid (ACC) is a non-proteinogenic amino acid[1] and is a member of 1-aminocycloalkanecarboxylic acids.[2]

Application

1-Aminocyclopropanecarboxylic acid (ACC) has been used as a substrate for determining ACC deaminase activity to study the plant growth-promoting characteristics of endophytic isolates obtained from Pteris vittata roots[3], cucurbit seeds.[4] It has also been used as an ethylene precursor to study the effect of high ethylene concentration on lateral root density (LRD) in sorghum brown midrib (bmr) mutants.[5]

Biochem/physiol Actions

1-Aminocyclopropanecarboxylic acid (ACC) is a partial agonist acting at the N-methyl-D-aspartate (NMDA) receptor glycine modulatory site.[6] ACC serves as a bio-synthetic precursor for the plant hormone ethylene.[1] Therefore, it also plays a vital role in plant development.[3] ACC exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.[7]

Antibody

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number
0000375977
0000355388
0000355387
0000317516
0000355387

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Sarita Tiwari et al.
Journal of environmental management, 180, 359-365 (2016-06-04)
Mitigation of arsenic (As) pollution is a topical environmental issue of high R&D priority. The present investigation was carried out to isolate As resistant endophytes from the roots of Indian ecotype Pteris vittata and characterize their As transformation and tolerance
Y A Kolesnikov et al.
Life sciences, 55(18), 1393-1398 (1994-01-01)
1-Aminocyclopropane carboxylic acid (ACPC), a partial agonist of the glycine site on the NMDA receptor, prevents tolerance to the mu opioid morphine and the delta ligand [D-Pen2,D-Pen5]enkephalin (DPDPE) when co-administered with the opioid. In contrast, ACPC does not significantly influence
Valentin Marquis et al.
Plant, cell & environment, 43(6), 1558-1570 (2020-03-13)
Jasmonate synthesis and signalling are essential for plant defense upregulation upon herbivore or microbial attacks. Stress-induced accumulation of jasmonoyl-isoleucine (JA-Ile), the bioactive hormonal form triggering transcriptional changes, is dynamic and transient because of the existence of potent removal mechanisms. Two
Joanna K Polko et al.
Frontiers in plant science, 10, 1602-1602 (2020-01-11)
1-Aminocyclopropane 1-carboxylic acid (ACC) is the direct precursor of the plant hormone ethylene. ACC is synthesized from S-adenosyl-L-methionine (SAM) by ACC synthases (ACSs) and subsequently oxidized to ethylene by ACC oxidases (ACOs). Exogenous ACC application has been used as a
Lorenzo Poncini et al.
PloS one, 12(10), e0185808-e0185808 (2017-10-04)
Plants interpret their immediate environment through perception of small molecules. Microbe-associated molecular patterns (MAMPs) such as flagellin and chitin are likely to be more abundant in the rhizosphere than plant-derived damage-associated molecular patterns (DAMPs). We investigated how the Arabidopsis thaliana
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