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D1878

Sigma-Aldrich

2,6-Dichloroindophenol sodium salt hydrate

Powder, BioReagent

Sinónimos:

2,6-Dichloro-N-(4-hydroxyphenyl)-1,4-benzoquinoneimine sodium salt, 2,6-Dichlorobenzenone-indophenol sodium salt, 2,6-Dichlorophenolindophenol sodium salt hydrate, DCIP, DPIP

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5 G
MXP 1,972.00
25 G
MXP 6,491.00

MXP 1,972.00

Fecha estimada de envío26 de marzo de 2025

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5 G
MXP 1,972.00
25 G
MXP 6,491.00

About This Item

Fórmula empírica (notación de Hill):
C12H6Cl2NNaO2 · xH2O
Número de CAS:
1266615-56-8
Peso molecular:
290.08 (anhydrous basis)
Beilstein/REAXYS Number:
3641229
EC Number:
210-640-4
MDL number:
MFCD00150014
UNSPSC Code:
12171500
PubChem Substance ID:
57654075
NACRES:
NA.47

MXP 1,972.00

Fecha estimada de envío26 de marzo de 2025

Solicitar un pedido a granel

Nombre del producto

2,6-Dichloroindophenol sodium salt hydrate, suitable for vitamin C determination, BioReagent

product line

BioReagent

Quality Level

200

form

powder

solubility

H2O: soluble 10 mg/mL, clear, blue to very deep blue

suitability

suitable for vitamin C determination

application(s)

diagnostic assay manufacturing
food and beverages
hematology
histology

storage temp.

room temp

SMILES string

O.[Na+].[O-]c1ccc(cc1)\N=C2/C=C(Cl)C(=O)C(Cl)=C2

InChI

1S/C12H7Cl2NO2.Na.H2O/c13-10-5-8(6-11(14)12(10)17)15-7-1-3-9(16)4-2-7;;/h1-6,16H;;1H2/q;+1;/p-1

InChI key

XHSOLXWCGCVQHE-UHFFFAOYSA-M

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General description

2,6-Dichloroindophenol sodium salt hydrate is a blue redox dye.

Application

2,6-Dichloroindophenol sodium salt hydrate is suitable for vitamin C determination. 2,6-Dichloroindophenol (DCIP) may be used in the following studies:
  • As redox dye to investigate the efficiency of gold nanoparticles (Au-NP) for enzymatic activity of glucose oxidase (GOx).[1]
  • To compose UVB specific dosimeter.[2]
  • Quantification of vitamin C (L-ascorbic acid) in fruit juices.[3]
  • As substrate in NQO1 assay to investigate the liver cytosolic NQO1 activity spectrophotometrically.[4]
  • Mitochondrial succinate CoQ oxidoreductase (complex II) activity assay.[5]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
BCCK3015
BCCH8797
BCCD6459
BCCD6463
BCCD6464

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Spectrophotometric evaluation of gold nanoparticles as red-ox mediator for glucose oxidase.
Ramanaviciene A, et al.
Sensors and Actuators B, Chemical, 137(2), 483-489 (2009)
Misty Prince et al.
Toxicology letters, 185(3), 180-186 (2009-01-20)
Naturally occurring coumarins possess anti-carcinogenic activities in part by inducing carcinogen-detoxifying enzymes glutathione S-transferase (GST) and/or NAD(P)H quinone oxidoreductase (NQO1). Our goal was to determine whether citrus coumarins induce hepatic GST and/or NQO1 via activation of Nrf2 and the antioxidant
Hanit Brenner-Lavie et al.
Biochimica et biophysica acta, 1777(2), 173-185 (2007-11-13)
Deleterious effects of dopamine (DA) involving mitochondrial dysfunction have an important role in DA-associated neuronal disorders, including schizophrenia and Parkinson's disease. DA detrimental effects have been attributed to its ability to be auto-oxidized to toxic reactive oxygen species. Since, unlike
Andrew Mills et al.
The Analyst, 134(5), 845-850 (2009-04-22)
A UVB specific dosimeter is described comprising: a redox dye (2,6-dichloroindophenol, DCIP), a semiconductor (tin(IV) oxide, SnO(2)) and a sacrificial electron donor (glycerol) dispersed in a polymer (hydroxy ethyl cellulose, HEC) film. The dosimeter is blue in the absence of
Further insights toward vitamin c determination and stability proposal of a new quantification method
Vieira CA, et al.
Biosci., 26(2), 296-304 (2010)
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Questions

1–8 of 8 Questions  

  1. Has Sigma Aldrich performed solution stability studies for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. No. Unfortunately, we have not performed solution stability studies on this product.

      Helpful?

  2. Has Product D1878, 2,6-Dichloroindophenol sodium salt hydrate, been used as a pH or redox indicator?

    1 answer

    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt in acid is  red and blue in alkali. The product is colorless when reduced.

      Helpful?

  3. Other than use as a reagent for determination of Vitamin C, are there other reported uses of Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. Yes. Conn's Biological Stains indicates Dichloroindophenol sodium salt has been used as an electron receptor, for use in demonstrating NADPH diaphorase and to stain glutathione reductase electrophoresis gels.

      Helpful?

  4. Are there published references for Dichloroindophenol sodium salt being used for the determination of Vitamin C?

    1 answer

    1. Yes. Please see: W. Horowitz ed. Official Methods of Analysis of the AOAC Washington D.C. , 777, (1970) and  K. Hiromi et al., Anal. Biochem. 101, 421, (1980).

      Helpful?

  5. Are there substances known to interfere in Vitamin C determination?

    1 answer

    1. Yes. Interfering substances are ferrous, stannous, and cuprous sulfite or thiosulfate ions, and SO2.

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  6. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  7. What is the solubility for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. During quality control testing, Sigma Aldrich tests solubility at 10 mg/mL in water.  Conn's Biological Stains, 10th Edition states that dichloroindophenol sodium salt is soluble up to 3% in water and up to 2% in ethanol.

      Helpful?

  8. Are the absorbance maxima and the extinction coefficients available for Product D1878, 2,6-Dichloroindophenol sodium salt hydrate?

    1 answer

    1. Our Analytical Department has run absorbance spectra on many lots of D1878. Using 0.1 M phosphate buffer, pH 8.3 as the solvent, absorbance maxima in the range of 600-605 nm and a mM extinction coefficient of 18.0-19.7 have been reported.

      Helpful?

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