1314009

Hydrochlorothiazide

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
• Empirical Formula (Hill Notation): C₇H₈ClN₃O₄S₂
• CAS Number: 58-93-5
• Molecular Weight: 297.74
• NACRES: NA.24
• PubChem Substance ID: 329750021
• UNSPSC Code: 41116107
• MDL number: MFCD00051765

Properties

• grade: pharmaceutical primary standard
• API family: hydrochlorothiazide
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: NS(=O)(=O)c1cc2c(NCNS2(=O)=O)cc1Cl
• InChI: 1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
• InChI key: JZUFKLXOESDKRF-UHFFFAOYSA-N
• Gene Information: human ... SLC12A3(6559)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Hydrochlorothiazide USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock, system suitability, Hydrochlorothiazide standard solutions for assay, performance, and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):

• Hydrochlorothiazide Capsules
• Amiloride Hydrochloride and Hydrochlorothiazide Tablets
• Captopril and Hydrochlorothiazide Tablets

Biochem/physiol Actions

Carbonic anhydrase inhibitor

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H351
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2
• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable