P8296

5-Phospho-D-ribose 1-diphosphate pentasodium salt

≥75% (HPLC)

• Synonym(s): α-D-Ribosyl diphosphate 5-phosphate pentasodium salt, 5-Phospho-α-D-ribosyl diphosphate, 5-Phosphoribosyl 1-pyrophosphate pentasodium salt, P-Rib-PP, PRPP pentasodium salt
• Empirical Formula (Hill Notation): C₅H₈Na₅O₁₄P₃
• CAS Number: 108321-05-7
• Molecular Weight: 499.98
• UNSPSC Code: 12352201
• NACRES: NA.25
• PubChem Substance ID: 24898743
• MDL number: MFCD32182529
• Beilstein/REAXYS Number: 6043637

Properties

• Quality Segment: 300
• assay: ≥75% (HPLC)
• form: powder
• impurities: <18% water (Karl Fischer)
• color: white
• solubility: water: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@H](O[C@@H]1COP(O)([O-])=O)OP([O-])(=O)OP([O-])([O-])=O
• InChI: 1S/C5H13O14P3.4Na/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13;;;;/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13);;;;/q;4*+1/p-4/t2-,3-,4-,5?;;;;/m1..../s1
• InChI key: QZAPPJHVNYCTAX-CKJQBBATSA-J

Description

General description

Substrate for phosphoribosyltransferases in the synthesis of nucleotides.

Application

Pentasodium salt has been used in a study to assess the relationship between the muscarinic receptor cationic current and internal calcium in guinea-pig jejunal smooth muscle cells. [1] It has also been used in a study to investigate inhibitors of the bacterial cell wall biosynthesis of the enzyme Mur D. [2]

Analysis Note

Purity ≥ 75% based on an assay system using orotidine-5′-phosphate pyrophosphorylase and orotidine-5′-phosphate decarboxylase mixed enzymes.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• pictograms: GHS08
• signalword: Warning
• hcodes: H371
• pcodes: P260
• Hazard Classifications: STOT SE 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves