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About This Item
经验公式（希尔记法）:
C26H41N3O5
CAS号:
分子量:
475.62
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.32
推荐产品
產品線
SAFC Hitech®
品質等級
化驗
≥95% (HPLC)
形狀
powder
溶解度
DMSO: soluble
儲存溫度
−20°C
SMILES 字串
O=C(N[C@H](CC(C)C)C(N[C@H](C=O)CC(C)C)=O)[C@H](CC(C)C)NC(OCC1=CC=CC=C1)=O
InChI
1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22+,23-/m0/s1
InChI 密鑰
TZYWCYJVHRLUCT-ZRBLBEILSA-N
基因資訊
human ... CTSB(1508) , NFKB1(4790) , PSMA1(5682)
生化／生理作用
MG-132（R）是一种有效的膜透性蛋白酶体抑制剂。以10μM的浓度，它诱导PC12细胞中的神经突向外生长。BXI-132(R)可阻断聚（ADP-核糖）聚合酶的切割和胸腺细胞的凋亡。然而，MG-132（R）还可激活c-Jun N-末端蛋白激酶（JNK-1），其可响应细胞应激而启动细胞凋亡。蛋白酶体抑制可诱导热休克蛋白mRNA的积累、热休克蛋白的激活、以及增强各种细胞类型中的耐热性。
法律資訊
SAFC Hitech is a registered trademark of Sigma-Aldrich Co. LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
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