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Merck
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Key Documents

P4154

Sigma-Aldrich

聚肌苷酸 钾盐

Homopolymer

别名:

聚（I） 钾盐

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About This Item

CAS号:
26936-41-4
MDL號碼:
MFCD00131982
分類程式碼代碼:
41106305
NACRES:
NA.51

生物源

synthetic (organic)

品質等級

200

化驗

≥98% (TLC)

形狀

lyophilized powder

溶解度

water: 4.80-5.20 mg/mL, clear to hazy, colorless to faintly yellow

儲存溫度

−20°C

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應用

聚肌苷酸（聚（I））是一种肌苷的均聚物，其可与聚胞苷酸（聚（C））一起形成双链均聚物（聚（I）·聚（C））。 TLR3 识别双链 RNA，并且是针对病毒病原体的免疫应答的主要效应分子。（Poly（I）•Poly（C））被用作研究 TLR3 水平的细胞信号传导的模型 RNA。Poly（IC）是一种 TRIF 依赖性 toll 样受体-3（TLR3）配体。

準備報告

通过多核苷酸磷酸化酶法从 IDP 制备。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Gennady Dvoryanchikov et al.
Nature communications, 8(1), 760-760 (2017-10-04)
Taste buds are innervated by neurons whose cell bodies reside in cranial sensory ganglia. Studies on the functional properties and connectivity of these neurons are hindered by the lack of markers to define their molecular identities and classes. The mouse
Xingbo Wang et al.
Veterinary microbiology, 251, 108895-108895 (2020-10-31)
RNA binding ability and cellular distribution are important for nonstructural protein 1 (NS1) of influenza A virus to act as a viral regulatory factor to control virus life cycle. In this study, we identified that the N-terminal residues 19-21 of
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo.
Packiriswamy N, Parvataneni S, Parameswaran N.
Cellular Immunology, 107-111 (2011)
Caiqi Ma et al.
International journal of oncology, 54(2), 572-584 (2018-11-30)
Gastric cancer is one of the most malignant tumor types, and its metastasis is a notable cause of mortality. Among the methods of tumor metastasis, lymphatic metastasis is the predominant one in gastric cancer. A previous study reported that the
Activation of chemokine and inflammatory cytokine response in HCV-infected hepatocytes depends on TLR3 sensing of HCV dsRNA intermediates.
Li K, Li NL, Wei D, Pfeffer SR, et al.
Hepatology, 55(3), 666-675 (2011)
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