价格与库存信息目前不能提供
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Amino Acid Sequence
H-Ile-Ser-Gln-Ala-Val-His-Ala-Ala-His-Ala-Glu-Ile-Asn-Glu-Ala-Gly-Arg-OH
一般描述
卵清蛋白（323-339）是由B细胞表位环绕的蛋清蛋白，被特异性IgE抗体结合。除此之外，它还含有CD4+ T细胞表位。[1]
该肽是卵清蛋白的第II类主要MHC限制性T细胞表位，用于研究免疫性过敏反应，如哮喘、食物过敏等。
应用
卵清蛋白（323-339）（鸡，日本鹌鹑）已被用于诱导小鼠过敏性哮喘。[2]
生化/生理作用
卵清蛋白（OVA）肽323-339在隔离的BALB/c小鼠体内介导25-35％的T细胞对完整OVA的反应。OVA 323-339被广泛用于测定第II类主要组织相容性复合体（MHC）-肽结合特征和T细胞活化特征。[1]
在两个功能不同的辅助因子的帮助下，卵清蛋白（323-339）肽可与组织相容性复杂的II类I-A（d）蛋白结合。[3]
外形
由0.1％ TFA水溶液冷冻干燥而得
其他说明
从0.1％ TFA的H2O溶液冷冻干燥而得
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
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Impressive clinical benefit is seen in clinic with PD-1 inhibitors on portion of cancer patients. Yet, there remains an urgent need to develop effective synergizers to expand their clinical application. Tumor-associated macrophage (TAM), a type of M2-polarized macrophage, eliminates or
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Asthma is a chronic disease, which is harmful to the health of the body and the quality of life. Supplementation of Lactobacillus can affect the immune environment of the lungs through the gut-lung axis. This study aimed to explore the
Haruyo Nakajima-Adachi et al.
Bioscience, biotechnology, and biochemistry, 76(10), 1979-1981 (2012-10-11)
The epitopes for OVA323-339-specific CD4⁺T cells from OVA23-3 food allergy model and DO11.10 tolerant induction model mice were analyzed. We found that OVA23-3 CD4⁺T cells recognized the N-terminal region, showing strong proliferation and the Th2-phenotype, and that DO11.10 CD4⁺T cells
Ovalbumin(323-339) peptide binds to the major histocompatibility complex class II I-A(d) protein using two functionally distinct registers
McFarland BJ, et al.
Biochemistry, 38(50), 16663-16670 (1999)
Min Liu et al.
Immunity, inflammation and disease, 11(2), e730-e730 (2023-02-18)
Asthma is a chronic respiratory disease with an increasing incidence every year. microRNAs (miRNAs) have been demonstrated to have implications for asthma. However, limited information is available regarding the effect of miR-124-3p on this disease. Therefore, this study aimed to
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