价格与库存信息目前不能提供
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生物来源
bovine
方案
≥90% (SDS-PAGE)
表单
lyophilized powder
分子量
18.4 kDa
储存条件
(Keep container tightly closed in a dry and well-ventilated place)
技术
activity assay: suitable
溶解性
water: 1 mg/mL, clear, colorless to faintly yellow
UniProt登记号
储存温度
−20°C
基因信息
cow ... MBP(618684)
一般描述
应用
用作激酶底物。
生化/生理作用
髓磷脂碱性蛋白（MBP）在髓鞘的形成中起重要作用，并且与各种神经障碍有关。髓磷脂碱性蛋白作为自身免疫疾病实验性变应性脑脊髓炎（EAE）中的抗原靶点。髓磷脂碱性蛋白在细胞骨架更新和膜延伸中起重要作用。此外，它还参与 Fyn 介导的信号途径、磷酸肌醇的隔离和钙稳态的调节。[8]髓磷脂碱性蛋白作为丝裂原活化蛋白激酶（MAP）激酶的体外底物起作用，并有助于酶的纯化和功能研究。[9]MBP是一种潜在的神经受体。它能刺激体外淋巴细胞的增殖。MBP作为底物在丝裂原活化蛋白（MAP）)激酶激活通路中起关键作用。[10]MBP可基于淋巴细胞刺激检测癌症。它被用于一些免疫学研究。MBP还有助于保存髓鞘内的脂质：蛋白质组织。[2]
髓鞘碱性蛋白基因突变可引起髓鞘发育不良。用于诱导实验无菌性炎症。
质量
可能含有微量尿素-甘氨酸缓冲液盐。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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