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L2145

Sigma-Aldrich

L-亮氨酸-7-氨基-4-甲基香豆素 盐酸盐

fluorogenic, ≥98% (TLC), powder

别名:

H-L-Leu-AMC HCl

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About This Item

经验公式（希尔记法）:
C16H20N2O3 · HCl
CAS号:
62480-44-8
分子量:
324.80
MDL编号:
MFCD00043262
UNSPSC代码:
12352204
PubChem化学物质编号:
24896303
NACRES:
NA.32

产品名称

L-亮氨酸-7-氨基-4-甲基香豆素 盐酸盐,

方案

≥98% (TLC)

表单

powder

溶解性

methanol: 50 mg/mL, clear, colorless to faintly yellow

荧光

λex 327 nm; λem 349 nm (pH 8.0)
λex 380 nm; λem 440 nm (Reaction product)

储存温度

−20°C

SMILES字符串

Cl.CC(C)C[C@H](N)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1

InChI key

VCRXITKKWBOQRZ-ZOWNYOTGSA-N

一般描述

L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐(Leu-AMC)是一种荧光肽基底物，用于测定亮氨酸氨肽酶活性，广泛存在于天然水生体系中。它是一种细菌蛋白水解酶。

应用

L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐(Leu-AMC)用于作为底物类似物，测定亮氨酸氨肽酶活性。
L-亮氨酸-7-酰胺基-4-甲基香豆素盐酸盐已被用于:
  • 作为荧光土壤测定的底物
  • 测定恶性疟原虫 M1 （PfA-M1）和 PfA-M17 酶的亮氨酸氨基肽酶活性

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM8046
BCCL8090
BCCK0769
BCCG2323
BCCD7189

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