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Merck
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文件

M3633

Sigma-Aldrich

4-甲基伞形酮基β-D-葡萄糖苷

β-glucosidase substrate, fluorogenic, ≥99% (HPLC), powder

别名:

MUD

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About This Item

经验公式（希尔记法）:
C16H18O8
CAS号:
18997-57-4
分子量:
338.31
Beilstein:
94672
EC號碼:
242-736-7
MDL號碼:
MFCD00063694
分類程式碼代碼:
12352204
PubChem物質ID:
24896859
NACRES:
NA.32

product name

4-甲基伞形酮基β-D-葡萄糖苷, β-glucosidase substrate

化驗

≥99% (HPLC)

形狀

powder

溶解度

DMF: 50 mg/mL, clear, colorless to faintly yellow

螢光

λex 316 nm; λem 372 nm (pH 9.1)
λex 360 nm; λem 449 nm (Reaction product)

儲存溫度

−20°C

SMILES 字串

CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1

InChI 密鑰

YUDPTGPSBJVHCN-YMILTQATSA-N

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應用

4-甲基伞形酮基β-D-葡萄糖苷可用来作为以下反应的底物：
  • 原发性海马神经元富含溶菌酶部分葡糖神经酰胺酶β 酶活性分析
  • 酵母发酵过程中β-葡萄糖苷酶分析
  • 巨噬细胞细胞系(RAW)中的葡萄糖脑苷脂酶1（GBA1）-相关葡萄糖苷酶活性分析

生化／生理作用

4-甲基伞形酮基β-D-葡萄糖苷是一种合成糖苷酶底物。它可用作来自肠球菌的葡萄糖苷酶底物。

其他說明

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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An Improved Helferich Method for the alphabeta-Stereoselective Synthesis of 4-Methylumbelliferyl Glycosides for the Detection of Microorganisms
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Mitochondrial dysfunction and mitophagy defect triggered by heterozygous GBA mutations
Li H, et al.
Autophagy, 15(1), 113-130 (2019)
A Rashidi et al.
Bone marrow transplantation, 51(12), 1561-1564 (2016-08-16)
Post-transplant cyclophosphamide (PT-Cy) is the backbone of GvHD prophylaxis following haploidentical hematopoietic cell transplantation (haplo-HCT). PT-Cy has also been used in matched related (MRD) and unrelated (MUD) settings. It is not known whether outcomes are similar between haplo-HCT and MRD/MUD
Assessing microbial safety of drinking water improving approaches and methods: Improving approaches and methods, 253-253 (2003)
Cornelis N De Jong et al.
PloS one, 12(10), e0187184-e0187184 (2017-10-27)
Acute graft-versus-host disease (aGVHD) is an important complication of allogeneic stem cell transplantation (alloSCT). High dose glucocorticosteroids, are currently recommended as first-line treatment for grade II-IV aGVHD resulting in overall complete responses (CR) in 40%-50% of patients. No standard second-line
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