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Merck
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文件

I9646

Sigma-Aldrich

IL-6 mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

mIL-6, IL-6

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About This Item

MDL號碼:
MFCD01656039
分類程式碼代碼:
12352202
NACRES:
NA.77

product name

白介素 -6 来源于小鼠, IL-6, recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, carrier free

生物源

mouse

品質等級

200

重組細胞

expressed in E. coli

化驗

≥97% (SDS-PAGE)

形狀

lyophilized powder

效力

0.02-0.2 ng/mL EC50

品質

endotoxin tested

分子量

~21.7 kDa

包裝

pkg of 5 and 25 μg

技術

cell culture | mammalian: suitable

雜質

≤1.0EU/mg

顏色

white

UniProt登錄號

P08505

儲存溫度

−20°C

基因資訊

mouse ... Il6(16193)

相关类别

生化／生理作用

白细胞介素-6 (IL-6) 是最初在双链 RNA 刺激的细胞培养基中发现的一种多功能蛋白。IL-6 似乎直接参与了感染和损伤后发生的反应，并可能证明在调节急性期反应方面与 IL-1 和 TNF-α同样重要。据报道，IL-6 由成纤维细胞、活化的 T 细胞、活化的单核细胞或巨噬细胞以及内皮细胞产生。作用于多种细胞，包括成纤维细胞、髓系祖细胞、T 细胞、B 细胞和肝细胞。如许多同义词所示，IL-6 诱导多种效应：浆细胞瘤生长因子 (PCT-GF)、干扰素-β-2（IFN-β 2 ）、单核细胞来源的人 B 细胞生长因子、B 细胞刺激因子 (BSF-2)、肝细胞刺激因子 (HSF)、白细胞介素杂交瘤/浆细胞瘤-1 (IL-HP1)。此外，IL-6 似乎在 T 淋巴细胞增殖中与 IL-2 相互作用。IL-6 还可增强 IL-3 对多潜能造血祖细胞的增殖作用。

外觀

从不含添加剂的无菌过滤溶液中冻干。

分析報告

重组小鼠IL-6的生物学活性已通过使用T1165.85.2.1细胞经过细胞增殖试验进行测定。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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