推荐产品
生物源
sheep
共軛
unconjugated
抗體表格
purified immunoglobulin
等級
reagent grade
化驗
≥95% (SDS-PAGE)
形狀
essentially salt-free, lyophilized powder
同型
IgG
溶解度
saline: 1 mg/mL at -20 °C (Repeated freezing and thawing is not recommended.)
儲存溫度
2-8°C
正在寻找类似产品? 访问 产品对比指南
一般說明
IgG 有 4 种同种型 IgG1、IgG2、IgG3 和 IgG4。它包含 4 个多肽链，由 2 条相同的 50 kDa γ 重（H）链和 2 条相同的 25 kDa κ或 λ 轻（L）链组成，它们通过链间二硫键连接。
應用
纯化的 IgG 可用作各种免疫测定中的参考抗原、标准品、封闭剂或包被蛋白，包括 ELISA、斑点免疫结合、蛋白免疫印迹、免疫扩散、免疫沉淀和免疫电泳等。其他应用包括作为制备免疫原和固相免疫吸附剂的起始材料。
生化／生理作用
IgG 介导经胎盘转运并参与二次免疫反应。IgG 激活补体系统的经典途径。它中和病毒颗粒和毒素。IgG 在抗体依赖性细胞介导的细胞毒性（ADCC）和吞噬作用中起关键作用。它可能与过敏有关。它具有最长的血清半衰期。
IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌，存在于血液和细胞外液中，可防止细菌、真菌和病毒引起的感染。母体IgG可通过胎盘转移至胎儿，胎盘对新生儿免疫防御感染至关重要。
分析報告
蛋白质浓度应在重组后通过 280 nm 处的吸光度（E1%/280 = 14）测定。
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Deepmala Karmakar et al.
Carcinogenesis, 41(12), 1767-1780 (2020-05-10)
Previously, our laboratory demonstrated that a deregulated E2F5/p38/SMAD3 axis was associated with uncontrolled cellular proliferation in prostate cancer (PCa). Here, we investigate the role of E2F5 in PCa in further details. RNAi-mediated E2F5 knockdown and pathway-focused gene expression profiling in
Agnieszka Gambus et al.
Cell cycle (Georgetown, Tex.), 12(8), 1225-1232 (2013-03-23)
Hexameric complexes of the six related Mcm2-7 proteins form the core of the replicative helicase. Two other proteins, Mcm8 and Mcm9, with significant homology to Mcm2-7 were first shown to play distinct roles during DNA replication in Xenopus laevis egg
Bijurica Chakraborty et al.
EBioMedicine, 37, 442-452 (2018-10-20)
Plasmodium falciparum and Plasmodium vivax are two major parasites responsible for malaria which remains a threat to almost 50% of world's population despite decade-long eradication program. One possible reason behind this conundrum is that the bases of clinical variability in
Kai Kessenbrock et al.
The Journal of clinical investigation, 118(7), 2438-2447 (2008-06-24)
Neutrophil granulocytes form the body's first line of antibacterial defense, but they also contribute to tissue injury and noninfectious, chronic inflammation. Proteinase 3 (PR3) and neutrophil elastase (NE) are 2 abundant neutrophil serine proteases implicated in antimicrobial defense with overlapping
S J Peacock et al.
Microbiology (Reading, England), 145 ( Pt 12), 3477-3486 (2000-01-08)
Adhesion of Staphylococcus aureus to human endothelial cells is implicated in the pathogenesis of invasive staphylococcal disease. The adhesion to endothelial cells of isogenic mutants defective in defined surface structures was studied. Three strains of S. aureus defective in fibronectin-binding
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门