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I4506

Sigma-Aldrich

IgG 来源于人类血清

reagent grade, ≥95% (SDS-PAGE), essentially salt-free, lyophilized powder

别名:

人 IgG

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About This Item

MDL编号:
MFCD00163923
UNSPSC代码:
12352203
NACRES:
NA.46

偶联物

unconjugated

等级

reagent grade

方案

≥95% (SDS-PAGE)

表单

essentially salt-free, lyophilized powder

组成

Protein, ≥90%

技术

ELISA: suitable
dot immunobinding: suitable
immunoelectrophoresis: suitable
western blot: suitable

储存温度

2-8°C

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相关类别

一般描述

纯化人IgG由混合的正常人血清经过分级分离和离子交换层析获得。本品以基本不含盐（不到1%钠）的冻干粉形式提供。

应用

以人血清IgG为标准品，在ELISA法测定中采用浓度为1.274 mg/ml, 检测牙 龈卟啉单胞菌 和 间质普雷沃氏菌的抗体反应。它被用在0.2 mg/ml浓度时对Vero、BHK、PtK2细胞的免疫标记。人血清IgG被用作抗-志贺氏菌 LPS抗体的SDS-PAGE的标准品。

生化/生理作用

IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它是由B细胞分泌的，存在于血液和细胞外液体中，可以防止细菌、真菌和病毒引起的感染。母体IgG通过胎盘传递给胎儿，该过程对新生儿免疫防御感染至关重要。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物应用。

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说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000440067
0000440066
0000440065
0000440065
0000440066

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Nils A Brechmann et al.
Biotechnology progress, 35(3), e2775-e2775 (2019-01-11)
High capacity magnetic protein A agarose beads, LOABeads PrtA, were used in the development of a new process for affinity purification of monoclonal antibodies (mAbs) from non-clarified CHO cell broth using a pilot-scale magnetic separator. The LOABeads had a maximum
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Journal of cell science, 130(24), 4168-4179 (2017-11-09)
Phagosome formation is a complicated process that requires spatiotemporally regulated actin reorganization. We found that RhoC GTPase is a critical regulator of FcγR-mediated phagocytosis in macrophages. Our live-cell imaging revealed that RhoC, but not RhoA, is recruited to phagocytic cups
Katinka Döhner et al.
Molecular biology of the cell, 13(8), 2795-2809 (2002-08-16)
After fusion of the viral envelope with the plasma membrane, herpes simplex virus type 1 (HSV1) capsids are transported along microtubules (MTs) from the cell periphery to the nucleus. The motor ATPase cytoplasmic dynein and its multisubunit cofactor dynactin mediate
Egil S Blix et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(5), 840-847 (2015-02-18)
Multiple myeloma (MM) is considered an incurable B cell malignancy, although many patients can benefit from high-dose therapy with autologous stem cell transplantation (ASCT) as a first-line treatment. In non-Hodgkin lymphoma (NHL), ASCT is usually performed after relapse with curative
Christopher Ashwood et al.
Journal of the American Society for Mass Spectrometry, 29(6), 1194-1209 (2018-04-01)
Profiling cellular protein glycosylation is challenging due to the presence of highly similar glycan structures that play diverse roles in cellular physiology. As the anomericity and the exact linkage type of a single glycosidic bond can influence glycan function, there
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