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一般說明
Haptoglobin (HP) is encoded by the gene mapped to human chromosome 16q22.2. There are two splice variants of the gene namely, HP1 and HP2.
免疫原
Human haptoglobin
應用
Anti-Haptoglobin antibody is suitable for use in Ouchterlony double diffusion (1:16) and immunoelectrophoresis.
Anti-Haptoglobin antibody produced in rabbit has been used in immunohistochemistry and western blotting.
生化／生理作用
Haptoglobin is an antioxidant protein that binds with hemoglobin. Haptoglobin primarily functions to inhibit oxidative damage induced by hemoglobin. Alterations in haptoglobin have been associated with the risk of diabetic vascular disorders such as retinopathy, nephropathy and cardiovascular diseases . Anti-Haptoglobin antibody is specific for haptoglobin in humans.
外觀
由 0.01M 的磷酸缓冲盐溶液 (pH 7.2) 冻干
重構
用 2ml 去离子水复原。
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Vivekananda Shetty et al.
Clinical proteomics, 9(1), 10-10 (2012-08-04)
In approximately 80% of patients, ovarian cancer is diagnosed when the patient is already in the advanced stages of the disease. CA125 is currently used as the marker for ovarian cancer; however, it lacks specificity and sensitivity for detecting early
Diminished acute phase response and increased hepatic inflammation of aged rats in response to intraperitoneal injection of lipopolysaccharide
Gomez C, et al.
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences, 63(12), 1299-1306 (2008)
Haptoglobin 2 allele associates with unstable carotid plaque and major cardiovascular events
Ijas P, et al.
Atherosclerosis, 230(2), 228-234 (2013)
Hagit Goldenstein et al.
Pharmacological research, 66(1), 1-6 (2012-04-03)
Haptoglobin (Hp) is a hemoglobin (Hb) binding protein whose major function is to prevent heme-iron mediated oxidation. The polymorphic nature of the Hp gene results in varying levels of antioxidant function associated with the protein products. Multiple clinical studies have
Farid M Nakhoul et al.
Nature clinical practice. Nephrology, 3(6), 339-344 (2007-05-26)
Vascular complications cause serious morbidity in patients with diabetes mellitus. Three such complications are nephropathy, retinopathy and accelerated atherosclerotic cardiovascular disease. There is currently scant evidence of a genetic marker that predicts which patients will have vascular complications. Oxidative stress
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