推荐产品
一般說明
Haptoglobin is a positive acute-phase plasma α2-sialoglycoprotein, and exists as three major phenotypes namely Hp 1-1, Hp 2-1, and Hp 2-2. Haptoglobin is composed of heavy β- (40 kDa) and light α- (α1= 8.9kDa and α2= 16kDa) chains. Hp 1-1 is the smallest phenotype with a molecular weight of 86kDa, and is composed of only α1.
生化／生理作用
Haptoglobin functions as an antioxidant by binding free hemoglobin, and eliminates it from circulation to prevent iron loss and renal injury following hemolysis. It is responsible for maintaining the helper T-cell type 1 and type 2 (Th1/Th2) balance, and functions as an immunosuppressor of lymphocyte function. It also functions as an angiogen and anti-inflammatory agent. Hp 1-1 phenotype is most effective in binding free hemoglobin and preventing inflammatory responses linked with free hemoglobin. Studies show that all the three phenotypes of haptoglobin are involved in idiopathic generalized epilepsy.
外觀
Lyophilized as a salt-free solid.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Haptoglobin phenotypes in epilepsy.
Sadrzadeh SM, et al.
Clinical Chemistry, 50(6), 1095-1097 (2004)
Haptoglobin phenotypes in health and disorders.
Sadrzadeh SM, Bozorgmehr J, et al.
American Journal of Clinical Pathology, 121, S97-104 (2004)
Determination of haptoglobin genotype in an Iranian population with idiopathic generalized epilepsy.
Al-Balaghee S et al
Reports of Biochemistry and Molecular Biology, 3(2), 51-55 (2015)
Fabiana Baganha et al.
International journal of molecular sciences, 23(21) (2022-11-12)
Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects. PC can be cleared by natural IgM antibodies and low levels of these antibodies have been associated with
Angelika Jochim et al.
eLife, 9 (2020-06-10)
Energy-coupling factor type transporters (ECF) represent trace nutrient acquisition systems. Substrate binding components of ECF-transporters are membrane proteins with extraordinary affinity, allowing them to scavenge trace amounts of ligand. A number of molecules have been described as substrates of ECF-transporters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门