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Merck

H4881

Sigma-Aldrich

氢化可的松琥珀酸酯 钠盐

≥90% (HPLC)

别名:

11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-hemisuccinate 钠盐, 氢化可的松 21-半琥珀酸酯 钠盐

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About This Item

经验公式(希尔记法):
C25H33NaO8
CAS号:
分子量:
484.51
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.77
价格与库存信息目前不能提供

生物源

synthetic (organic)

品質等級

化驗

≥90% (HPLC)

形狀

powder

溶解度

water: 50 mg/mL, clear, colorless to faintly yellow

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(COC(CCC([O-])=O)=O)=O)=C1.[Na+]

InChI

1S/C25H34O8.Na/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30;/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30);/q;+1/p-1/t16-,17-,18-,22+,23-,24-,25-;/m0./s1

InChI 密鑰

HHZQLQREDATOBM-CODXZCKSSA-M

基因資訊

human ... NR3C1(2908)

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應用

Hydrocortisone 21-hemisuccinate sodium salt has been used:
  • as a component of the maturation medium for hepatic differentiation[1]
  • in the corticosterone (CORT) treatment to study its effect on astrocyte-like neural stem cell proliferation in the area postrema of the adult mouse brain[2]
  • in cortisol incubation experiments to study the effect of cortisol on the expression and function of sodium-chloride cotransporter (NCC) in zebrafish embryos[3]

象形圖

Health hazard

訊號詞

Warning

危險聲明

防範說明

危險分類

Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Yuri Nambu et al.
Neuroscience letters, 748, 135732-135732 (2021-02-17)
The discovery of neural stem cells (NSCs) in the adult mammalian brain has provided insights into an extra level of brain plasticity. The proliferation and differentiation of NSCs is modulated by various physiological, pathological, and pharmacological stimuli. NSCs were recently
Chia-Hao Lin et al.
Molecular and cellular endocrinology, 422, 93-102 (2015-12-19)
In mammals, sodium/hydrogen exchanger (NHE) and sodium-chloride cotransporter (NCC) are expressed in renal tubules, and exhibit functional redundancy and mutual compensation in Na(+) uptake. In teleosts, the gills of the adult and skin of the embryonic stage function as external
Yuri Nambu et al.
Neuroscience letters, 748, 135732-135732 (2021-02-17)
The discovery of neural stem cells (NSCs) in the adult mammalian brain has provided insights into an extra level of brain plasticity. The proliferation and differentiation of NSCs is modulated by various physiological, pathological, and pharmacological stimuli. NSCs were recently
Influence Of Cortisol On The Attachment And Metamorphosis Of Larval Utterbackia Imbecillis On Bluegill Sunfish (Lepomis Macrochirus).
Dubansky, B., et al.
The Biochemical Journal, 220, 97-106 (2011)
Y Baert et al.
Human reproduction (Oxford, England), 35(5), 1029-1044 (2020-05-12)
Is it possible to co-culture and functionally link human liver and testis equivalents in the combined medium circuit of a multi-organ chip? Multi-organ-chip co-cultures of human liver and testis equivalents were maintained at a steady-state for at least 1 week and

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