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Merck
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文件

H0878

Sigma-Aldrich

肝素 锂盐 来源于猪肠粘膜

≥150 USP units/mg

别名:

Lithium acid heparin, Lithium heparinate

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About This Item

CAS号:
9045-22-1
MDL號碼:
MFCD00131308
分類程式碼代碼:
12352201
NACRES:
NA.25

生物源

Porcine intestinal mucosa

品質等級

200

形狀

powder

比活性

≥150 USP units/mg

顏色

off-white

溶解度

water: 40 mg/mL, clear, colorless to faint yellow or tan

正離子痕跡

Li: 3-4%

應用

diagnostic assay manufacturing
life science and biopharma
plasma purification
sample preparation

儲存溫度

room temp

InChI

1S/C14H25NO20S3/c1-29-9-7(17)10(35-38(26,27)28)14(34-11(9)12(18)19)33-8-4(3-31-37(23,24)25)32-13(30-2)5(6(8)16)15-36(20,21)22/h4-11,13-17H,3H2,1-2H3,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28)

InChI 密鑰

HXSDFQWQRCUQHF-UHFFFAOYSA-N

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相关类别

一般說明

Heparin lithium is a highly sulfated polysaccharide that belongs to the family of glycosaminoglycans with remarkable significance in the areas of cell culture, cancer biology, biochemical, and drug discovery research. Due to its interactions with proteins and cells, it is used to study molecular and cellular processes, tumor modeling, investigate binding interactions, and as a cell culture supplement, to maintain cell viability.

應用

Heparin lithium was used:
  • To validate photometric measurements in cell surface charge determination
  • As an anti-coagulant for laboratory studies
  • To study hypothermal stress on lactate metabolism
  • To study the effects of anticoagulants in direct membrane feeding assays
  • For 2D and 3D vitro cell culture in glioblastoma cell models
  • To prevent clot formation and tissue damage during mechanical probing of cardiac pacemaker cell embryonic patterning, a study that contributes to the broader area of cardiac tissue mechanics research and developmental biology

特點和優勢

  • Heparin with specific activity of ≥150 USP units/mg
  • Versatile and adaptable for a wide variety of laboratory and research applications

其他說明

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

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Determination of cell surface charge by photometric titration
Thethi K et al
Journal of Biochemical and Biophysical Methods, 34, 137-145 (1997)
The effect of anticoagulants in blood collection tubes on Plasmodium falciparum transmission in direct membrane feeding assays
Wouter G et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 116, 187- 189 (2022)
Chia-Hao Chang et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 248, 110744-110744 (2020-06-23)
The milkfish Chanos chanos, an economically important cultured marine species in Southeast Asia, exhibits stenothermal and euryhaline characteristics and huge mortality usually occurs during extreme cold weather in winter. Under conditions beyond optimal temperatures, ectothermic species experience an increase in
R B Shartau et al.
The Journal of experimental biology, 223(Pt 7) (2020-03-05)
Acute (<96 h) exposure to elevated environmental CO2 (hypercarbia) induces a pH disturbance in fishes that is often compensated by concurrent recovery of intracellular and extracellular pH (pHi and pHe, respectively; coupled pH regulation). However, coupled pH regulation may be limited
Beatriz Giesen et al.
Pharmaceutics, 13(2) (2021-03-07)
Gold nanoparticles (Au NPs) are studied as delivery systems to enhance the effect of the glutaminase1 inhibitor CB839, a promising drug candidate already in clinical trials for tumor treatments. Au NPs were synthesized using a bottom-up approach and covered with
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Glycosaminoglycan Sulfation and Signaling

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

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