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一般描述
2-氟-2-脱氧-D-葡萄糖无毒,是葡萄糖的结构类似物,显著抑制了糖基化。作为葡萄糖类似物,2-氟-2-脱氧-D-葡萄糖在大脑和心脏细胞中可被迅速摄取。
2-氟-2-脱氧-D-葡萄糖可以被细胞吸收,但不进行代谢性糖酵解。
2-氟-2-脱氧-D-葡萄糖可以被细胞吸收,但不进行代谢性糖酵解。
应用
2-氟-2-脱氧-D-葡萄糖被用作快速肿瘤检测的示踪剂。它被用作葡萄糖模拟物,以研究辐射和烧伤小鼠的葡萄糖摄取。肿瘤治疗研究使用FDG联合PET(正电子发射地形图)
生化/生理作用
抑制细胞糖基化的葡萄糖类似物。
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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Radiation exposure and burn injury have both been shown to alter glucose utilization in vivo. The present study was designed to study the effect of burn injury combined with radiation exposure on glucose metabolism in mice using [¹⁸F] 2-fluoro-2-deoxy-D-glucose (¹⁸FDG).
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