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Merck

F4641

Sigma-Aldrich

抗-人IgG3−FITC抗体,小鼠单克隆 小鼠抗

clone HP-6050, purified from hybridoma cell culture

别名:

单克隆抗 人 IgG3

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

mouse

共軛

FITC conjugate

抗體表格

purified immunoglobulin

抗體產品種類

secondary antibodies

無性繁殖

HP-6050, monoclonal

形狀

buffered aqueous solution

儲存條件

protect from light

技術

dot immunobinding: 1:64
particle immunofluorescence: 1:8

同型

IgG1

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

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一般說明

人免疫球蛋白G(IgG)有四个亚类:IgG1、IgG2、IgG3 和 IgG4,分别对应重链γ1、γ2、γ3和γ4。抗体的一级结构由二硫键连接两条重链并连接重链和轻链。IgG3为促炎性抗体,在病毒感染时最先出现,引发效应作用。

特異性

该抗体对人 IgG3 具有特异性,与其他 IgG 亚类不反应。IUIS/WHO 研究推荐该克隆在广泛的检测方案和技术中具有特异性和反应性。

應用

小鼠单克隆抗人 IgG3-FITC 抗体可用于免疫组化和间接免疫荧光。

外觀

0.01 M 磷酸盐缓冲液 (pH 8.0) 中的溶液,含 1% 灭活牛血清白蛋白和 15 mM 叠氮化钠。

儲存和穩定性

如需连续使用,可在 2-8 °C 下储存长达一个月。
对于长期储存,溶液可以工作等份冷冻。不推荐反复冻融。如果延长储存时间后出现轻微浑浊,使用前离心澄清。

其他說明

为了获得最佳结果,建议每个个体用户通过滴定法测定工作稀释液。

免責聲明

除非我们的产品目录或产品随附的其他公司文件中另有说明,否则我们的产品仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


分析证书(COA)

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Erdem Tüzün et al.
Acta neuropathologica, 118(6), 737-743 (2009-08-15)
We report the immunopathological analysis of the brain and tumor of two patients who died of anti-NMDAR-associated encephalitis, and of the tumor of nine patients who recovered. Findings included prominent microgliosis and deposits of IgG with rare inflammatory infiltrates in
Seroprevalence of human herpesvirus 6 in Andino Pune?os (Argentina)
Romagnoli, Pablo Alberto, et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 669-672 (2000)
Antibody structure, instability, and formulation.
Wang W, et al.
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
IgG Subclasses and Allotypes: From Structure to Effector Functions
Gestur V, et al.
Frontiers in Immunology (2014)
Tiffany N Caza et al.
Kidney360, 1(6), 491-500 (2020-04-21)
Common variable immunodeficiency (CVID) is one of the most common primary immunodeficiency syndromes, affecting one in 25,000-50,000 people. Renal insufficiency occurs in approximately 2% of patients with CVID. To date, there are no case series of renal biopsies from patients

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