所有图片(4)
About This Item
经验公式（希尔记法）:
C10H13NO4 · HCl
CAS号:
分子量:
247.68
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.77
推荐产品
product name
L -3,4-二羟基苯丙氨酸甲酯 盐酸盐, solid
形狀
solid
品質等級
顏色
white to off-white
儲存溫度
−20°C
SMILES 字串
Cl[H].COC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
InChI
1S/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H/t7-;/m0./s1
InChI 密鑰
WFGNJLMSYIJWII-FJXQXJEOSA-N
應用
L-3,4-二羟基苯丙氨酸甲酯盐酸盐用于：
- 治疗6-羟基多巴胺诱导的小鼠5-羟色胺神经元损伤
- 研究 B16F10 皮肤黑色素瘤细胞中酪氨酸酶活性
- 研究其对中脑神经元的神经保护作用
生化／生理作用
L-3,4-二羟基苯丙氨酸甲酯是 L-DOPA 的前体，可穿过血脑屏障。抗帕金森氏病药物 L-DOPA 甲酯在白血病和黑色素瘤中引发抗肿瘤功能。
注意
光敏性
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
其他客户在看
Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat
De Souza Silva MA, et al.
Journal of Neurochemistry, 68(1), 233-239 (1997)
Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H2 O2-induced oxidative stress
Zhong H, et al.
Royal Society of Chemistry Advances, 9(33), 18747-18757 (2019)
Fabrizio Stocchi et al.
Movement disorders : official journal of the Movement Disorder Society, 25(12), 1881-1887 (2010-07-30)
Melevodopa hydrochloride plus carbidopa in effervescent tablets (M/C) is a readily soluble antiparkinsonian tablet formulation. A total of 221 patients with Parkinson's disease and motor fluctuations entered a randomized, double-blind, double-dummy, controlled parallel group study, which compared the effectiveness of
3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of l-DOPA
Asanuma M and Miyazaki I
BMC Neuroscience, 17(1), 52-52 (2016)
Xinxin Yang et al.
International journal of nanomedicine, 7, 2077-2086 (2012-05-24)
Levodopa remains the most effective drug in the treatment of Parkinson's disease. However, long-term administration of levodopa induces motor complications, such as levodopa-induced dyskinesia. The mechanisms underlying levodopa-induced dyskinesia are not fully understood. In this study, we prepared levodopa methyl
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门