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Merck

C0166

Sigma-Aldrich

半胱氨酸-甘氨酸

≥85% (TLC), suitable fo HPLC

别名:

L-cysteinyl-glycine

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About This Item

经验公式(希尔记法):
C5H10N2O3S
CAS号:
分子量:
178.21
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.26

product name

半胱氨酸-甘氨酸, ≥85% (TLC)

化驗

≥85% (TLC)

形狀

solid

技術

HPLC: suitable

儲存溫度

−20°C

SMILES 字串

NC(CS)C(=O)NCC(O)=O

InChI

1S/C5H10N2O3S/c6-3(2-11)5(10)7-1-4(8)9/h3,11H,1-2,6H2,(H,7,10)(H,8,9)

InChI 密鑰

ZUKPVRWZDMRIEO-UHFFFAOYSA-N

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一般說明

半胱氨酰甘氨酸是一种二肽,为谷胱甘肽分解代谢的副产物。

應用

半胱氨酰甘氨酸用于对羟基汞苯甲酸(PHMB)的衍生化,用紫外可见二极管阵列检测器(RPLC-DAD)进行在线和连续的反相色谱校准。

生化/生理作用

L-半胱氨酸-L-甘氨酸 (Cys-Gly) 用于谷胱甘肽的稳态研究。Cys-Gly 是巯基稳态、氧化应激和金属管理领域研究的重要分子。
半胱氨酰甘氨酸是神经元中谷胱甘肽生物合成的前体。在过渡金属离子存在的条件下,有利于产生活性氧物质。正常的半胱氨酰甘氨酸水平对于维持正常细胞功能至关重要。

其他說明

谷胱甘肽片段

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Oral - Eye Irrit. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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其他客户在看

Sandra Osburn et al.
Journal of the American Society for Mass Spectrometry, 23(6), 1019-1023 (2012-03-01)
The radical cations of Cys-Gly and Gly-Cys were studied using ion-molecule reactions (IMR), infrared multiple-photon dissociation (IRMPD) spectroscopy, and density functional theory (DFT) calculations. Homolytic cleavage of the S-NO bond of nitrosylated precursors generated radical cations with the radical site
Dagmar Drogan et al.
Arteriosclerosis, thrombosis, and vascular biology, 30(10), 2053-2058 (2010-07-31)
To investigate the interrelation between plasma γ-glutamyltransferase (GGT) activity, cysteinyl-glycine (Cys-Gly) (ie, a thiol originating from GGT-mediated cleavage of glutathione), and oxidized low-density lipoprotein (oxLDL) with regard to myocardial infarction (MI) risk in a prospective study. Incident cases of MI
Purification and characterization of a Cys-Gly hydrolase from the gastropod mollusk, Patella caerulea
Cappiello M, et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 31(6), 1560-1565 (2016)
Pawinee Panpetch et al.
BMC plant biology, 21(1), 69-69 (2021-02-03)
Durian (Durio zibethinus L.) is a highly popular fruit in Thailand and several other Southeast Asian countries. It is abundant in essential nutrients and sulphur-containing compounds such as glutathione (GSH) and γ-glutamylcysteine (γ-EC). Cysteinylglycine (Cys-Gly) is produced by GSH catabolism
Rita Ferin et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 911, 15-20 (2012-12-12)
Alterations in the plasma aminothiols levels can be considered as important biomarkers for the diagnosis and screening of several human disorders, namely cardiovascular diseases. We aimed to optimize a rapid, sensitive and accurate RP-HPLC methodology with fluorescence detection, for the

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