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63535

Sigma-Aldrich

氯化锰 四水合物

BioUltra, for molecular biology, ≥99.0% (KT)

别名:

Manganese chloride tetrahydrate, Manganese dichloride tetrahydrate, MnCl2.4H2O

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About This Item

线性分子式:
MnCl2 · 4H2O
CAS号:
13446-34-9
分子量:
197.91
EC 号:
231-869-6
MDL编号:
MFCD00149792
UNSPSC代码:
12352302
PubChem化学物质编号:
57651943
NACRES:
NA.25
方案:
≥99.0% (KT)
等级:
for molecular biology
溶解性:
H2O: 0.5 M at 20 °C, clear, colorless

等级

for molecular biology

质量水平

200

产品线

BioUltra

方案

≥99.0% (KT)

杂质

DNases, none detected
 RNases, none detected
 insoluble matter, passes filter test
 phosphatases, none detected
 proteases, none detected

pH值（酸碱度）

4-6 (25 °C, 0.5 M in H2O)

mp

58 °C (lit.)

溶解性

H2O: 0.5 M at 20 °C, clear, colorless

痕量阴离子

sulfate (SO42-): ≤50 mg/kg

λ

0.5 M in H2O

紫外吸收

λ: 260 nm Amax: 0.01
λ: 280 nm Amax: 0.01

SMILES字符串

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

InChI key

CNFDGXZLMLFIJV-UHFFFAOYSA-L

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其他说明

在 DNA 拖尾-推荐用于 dC 和 dG 拖尾的 MnCl 2 缓冲液；在 RNA 逆转录中用耐热 DNA 聚合酶

警示用语：

Danger

危险声明

H301,H318,H373

危险分类

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

靶器官

Brain

储存分类代码

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

闪点(°F)

does not flash

闪点(°C)

does not flash

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM5039
BCCL6420
BCCH2663
BCCJ4597
BCCD2337

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T W Myers et al.
Biochemistry, 30(31), 7661-7666 (1991-08-06)
A recombinant DNA polymerase derived from the thermophilic eubacterium Thermus thermophilus (Tth pol) was found to possess very efficient reverse transcriptase (RT) activity in the presence of MnCl2. Many of the problems typically associated with the high degree of secondary
Nicholas Sofos et al.
Molecular cell, 79(5), 741-757 (2020-07-31)
Cmr-β is a type III-B CRISPR-Cas complex that, upon target RNA recognition, unleashes a multifaceted immune response against invading genetic elements, including single-stranded DNA (ssDNA) cleavage, cyclic oligoadenylate synthesis, and also a unique UA-specific single-stranded RNA (ssRNA) hydrolysis by the
Terminal transferase: use of the tailing of DNA and for in vitro mutagenesis.
G Deng et al.
Methods in enzymology, 100, 96-116 (1983-01-01)
Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
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