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Merck
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文件

E3876

Sigma-Aldrich

N -乙基马来酰亚胺

crystalline, ≥98% (HPLC)

别名:

NEM

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About This Item

经验公式（希尔记法）:
C6H7NO2
CAS号:
128-53-0
分子量:
125.13
Beilstein:
112448
EC號碼:
204-892-4
MDL號碼:
MFCD00005509
分類程式碼代碼:
12352106
PubChem物質ID:
24278420
NACRES:
NA.21

生物源

synthetic (organic)

品質等級

200

化驗

≥98% (HPLC)

形狀

crystalline

儲存條件

(Tightly closed. Dry. Keep in a well-ventilated place. )

技術

activity assay: suitable
co-immunoprecipitation (co-IP): suitable
immunoblotting: suitable

顏色

white to faint yellow

bp

210 °C (lit.)

mp

43-46 °C (lit.)

溶解度

ethanol: 50 mg/mL, clear to slightly hazy, colorless to faint yellow or tan

適合性

suitable for Western blot

應用

life science and biopharma

儲存溫度

2-8°C

SMILES 字串

CCN1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI 密鑰

HDFGOPSGAURCEO-UHFFFAOYSA-N

基因資訊

human ... KCNQ2(3785) , KCNQ4(9132) , KCNQ5(56479) , SLC6A3(6531) , SLC6A4(6532)

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應用

用于共价修饰蛋白质的半胱氨酸残基的试剂。

生化／生理作用

使 NADP 依赖性异柠檬酸脱氢酶和许多核酸内切酶失活的巯基烷化剂。
增强来自交感神经元的原生 M 通道的电流，并作为 KCNQ2、KCNQ4 和 KCNQ5 通道的开放剂。

準備報告

NEM 以 50mg/ml 的浓度溶于乙醇可得到透明的溶液。NEM 可溶于水（在 4ml 水中的溶解量 >50mg）；然而，水溶液却不稳定。水解速率为假一级，并显著依赖于 pH 值。

其他說明

如需了解生化试剂系列的更多信息，请填写此表。

象形圖

Skull and crossbonesCorrosion
GHS06,GHS05

訊號詞

Danger

危險分類

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

163.2 °F - closed cup

閃點（°C）

72.9 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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分析证书(COA)

Lot/Batch Number
0000391608
0000390102
0000387749
0000389503
0000368606

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