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04260

Sigma-Aldrich

N -乙基马来酰亚胺

purum p.a., ≥99.0% (HPLC)

别名:

NEM

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About This Item

经验公式（希尔记法）:
C6H7NO2
CAS号:
128-53-0
分子量:
125.13
Beilstein:
112448
EC 号:
204-892-4
MDL编号:
MFCD00005509
UNSPSC代码:
12352209
PubChem化学物质编号:
329747901
NACRES:
NA.26

等级

purum p.a.

方案

≥99.0% (HPLC)

灼烧残渣

≤0.05%

沸点

210 °C (lit.)

mp

43-46 °C (lit.)
43-46 °C

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Ca: ≤50 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
K: ≤100 mg/kg
Na: ≤100 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

储存温度

2-8°C

SMILES字符串

CCN1C(=O)C=CC1=O
CCN1C(=O)C=CC1=O

InChI

1S/C6H7NO2/c1-2-7-5(8)3-4-6(7)9/h3-4H,2H2,1H3

InChI key

HDFGOPSGAURCEO-UHFFFAOYSA-N

基因信息

human ... SLC6A3(6531) , SLC6A4(6532)

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应用

N-乙基马来酰亚胺已被用于测量与血浆蛋白结合的低分子量硫醇。
用于共价修饰蛋白质的半胱氨酸残基的试剂。

生化/生理作用

使 NADP 依赖性异柠檬酸脱氢酶和许多核酸内切酶失活的巯基烷化剂。
增强来自交感神经元的原生 M 通道的电流，并作为 KCNQ2、KCNQ4 和 KCNQ5 通道的开放剂。

象形图

Skull and crossbonesCorrosion
GHS06,GHS05

警示用语：

Danger

危险分类

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

163.2 °F - closed cup

闪点(°C)

72.9 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM8603
BCCM2417
BCCM2232
BCCK0315
BCCH5167

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