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Merck

27285

Sigma-Aldrich

乙二胺四乙酸 二钠盐 二水合物

meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0%

别名:

EDTA 二钠盐, EDTA-Na2, 乙二胺四乙酸Na2, 乙二胺四乙酸盐 二钠盐 二水合物, 二钠乙二胺四乙酸盐 二水合物, 依地酸钙钠

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About This Item

经验公式(希尔记法):
C10H14N2Na2O8 · 2H2O
CAS号:
分子量:
372.24
Beilstein:
3900609
EC號碼:
分類程式碼代碼:
12352107
PubChem物質ID:
NACRES:
NA.77
价格与库存信息目前不能提供

agency

tested according to BP
tested according to Ph. Eur.
tested according to USP

品質等級

法律遵循

tested according to FCC

化驗

99.0-101.0%

形狀

crystals

品質

meets analytical specification of Ph. Eur., BP, USP, FCC

反應適用性

reagent type: chelator

雜質

residual solvents, complies
≤0.001% cyanide (CN)
≤0.001% heavy metals (as Pb)
≤0.1% nitrilotriacetic acid (HPLC) (HPLC)

損耗

8.7-11.4% loss on drying, 200 °C, 3 h

pH值

4-5 (20 °C, 5%)

mp

248 °C (dec.) (lit.)

溶解度

water: soluble 100 g/L at 20 °C

負離子痕跡

chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤500 mg/kg

正離子痕跡

As: ≤1 mg/kg
Ca:, in accordance
Fe: ≤10 mg/kg
Pb: ≤10 mg/kg

應用

pharmaceutical (small molecule)

SMILES 字串

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

InChI 密鑰

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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一般說明

乙二胺四乙酸二钠盐二水合物或EDTA是广泛使用的二价阳离子如Ca⁺²的螯合剂。它可以抑制金属离子依赖性蛋白酶,如钙依赖性半胱氨酸蛋白酶。EDTA还可作为锌离子的螯合剂,抑制需要锌来活化的金属蛋白酶。

應用

乙二胺四乙酸二钠盐二水合物与 Na2HPO4 和柠檬酸一起用于制备 Na2EDTA-McIlvaine 缓冲液。[1]乙二胺四乙酸二钠盐二水合物的水溶液也已用于光催化制氢[2]
二价阳离子的螯合剂。 对需要二价阳离子发挥活性的酶,比如金属蛋白酶具有抑制作用。

其他說明

如需了解生化试剂系列的更多信息,请填写此表

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

標靶器官

Respiratory Tract

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Evaluation of EDTA as the chelator in the biuret reagent.
H Van Kley et al.
Clinical chemistry, 19(6), 621-623 (1973-06-01)
Solvent-free hydrothermal synthesis of anatase TiO2nanoparticleswith enhanced photocatalytic hydrogen production activity.
Ayad F. Alkaim
Applied Catalysis A: General, 466, 32- 37 (2013)
Sinan Akbayram et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 17(5), 494-496 (2010-06-10)
Ethylenediaminetetraacetic acid (EDTA)-dependent pseudothrombocytopenia (PTCP) is the phenomenon of a spurious low platelet count due to antiplatelet antibodies that cause platelet clumping in blood anticoagulated with EDTA. The aggregation of platelets in EDTA-dependent PTCP is usually prevented by other anticoagulants
Haruthai Sangjarusvichai et al.
Talanta, 79(4), 1036-1041 (2009-07-21)
In this report, we aimed to extend our previous efforts toward the evaluation of sulfonamides (SAs) with a boron-doped diamond (BDD) electrode. We improved this method by reducing the analysis time using a monolithic column coupled with amperometric detection to
Suli Huang et al.
PloS one, 10(2), e0117007-e0117007 (2015-02-07)
microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported.

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LC/LC-MS method identifies 8 aminoglycosides in pork using Discovery® DSC-18 SPE and Ascentis® Express C18 UHPLC, per Chinese standards.

Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the grade of Product No. 27285?

    1 answer
    1. Product 27285 is a reagent that meets the analytical specification of Ph. Eur., BP, USP, FCC. Ph.

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