推荐产品
生物源
mouse
品質等級
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
1C5H11, monoclonal
物種活性
human, mouse
技術
ELISA: suitable
flow cytometry: suitable
western blot: suitable
同型
IgG2b
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... TGFBR3(7049)
一般說明
Transforming growth factor beta receptor type 3 (TGF-beta receptor type 3 or TGFR-3), also known as Betaglycan or Transforming growth factor beta receptor III (TGF-beta receptor type III), and encoded by the gene name TGFBR3, is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG).
免疫原
Purified recombinant fragment of human TGFBR3 expressed in E. Coli
應用
Anti-TGFBR3, clone 1C5H11 Antibody is an antibody against TGFBR3 for use in western blotting, flow cytometry & ELISA.
Flow Cytometry Analysis: A 1:200-1:400 dilution from a representative lot detected TGFBR3 in MOLT4 cells.
ELISA: A representative lot was used on Control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
ELISA: A representative lot was used on Control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Tumor Markers
Tumor Markers
品質
Evaluated by Western Blotting in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.
Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected TGFBR3 in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.
Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected TGFBR3 in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.
標靶描述
~93 kDa observed. Uncharacterized bands may be observed in some lysate(s).
外觀
Unpurified
Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
儲存和穩定性
Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類(WGK)
nwg
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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