跳转至内容
Merck
所有图片(3)

文件

AB4326

Sigma-Aldrich

ISL-1抗体

from rabbit, purified by affinity chromatography

别名:

ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

horse, human, mouse

物種活性(以同源性預測)

sheep (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), bovine (based on 100% sequence homology)

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... ISL1(3670)

一般說明

胰岛因子1(ISL-1)是一种转录因子,在朗格汉斯胰岛的胚胎发生中发挥重要作用。它在肾上腺髓质和背根神经节的神经元亚群、视网膜内核和神经节细胞层、松果体和大脑某些区域中表达。在小鼠胚胎中,缺乏这种基因就无法进行神经管运动神经元的分化。最近,它被确定为心脏祖细胞谱系的标志物,该谱系能够分化为所有3种主要心脏细胞类型:心肌细胞、平滑肌和内皮细胞谱系。

特異性

基于100%的序列同源性,预测会与最常见的脊椎动物物种反应。
该抗体可识别ISL-1。

免疫原

KLH偶联线性肽,对应于人ISL-1。
表位:ISL-1的内部区域。

應用

ISL-1抗体是一种检测ISL-1(又称ISL LIM同源盒1、ISL1转录因子LIM/同源结构域)的兔多克隆抗体 & 已通过WB & IHC验证。
免疫组化分析:先前批次的1:300稀释液在小鼠胰腺组织中检测到ISL-1。

品質

通过蛋白质印迹法对K562细胞裂解液进行了评估。

蛋白质印迹分析:0.5 µg/mL的该抗体在10 µg K562细胞裂解液中检测到ISL-1。

標靶描述

~39 kDa

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

未找到合适的产品?  

试试我们的产品选型工具.

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Joseph A Bisson et al.
Developmental biology, 398(1), 80-96 (2014-12-09)
Wnt proteins regulate cell behavior via a canonical signaling pathway that induces β-catenin dependent transcription. It is now appreciated that Wnt/β-catenin signaling promotes the expansion of the second heart field (SHF) progenitor cells that ultimately give-rise to the majority of
Zane Zeier et al.
Experimental neurology, 271, 241-250 (2015-06-24)
A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products
Laura I Hudish et al.
Stem cell reports, 14(6), 1033-1043 (2020-05-11)
Human motor neuron (MN) diseases encompass a spectrum of disorders. A critical barrier to dissecting disease mechanisms is the lack of appropriate human MN models. Here, we describe a scalable, suspension-based differentiation system to generate functional human MN diseases in
Shuichi Kato et al.
Nagoya journal of medical science, 77(1-2), 253-263 (2015-03-24)
Transplantation of motoneurons (MN) into the peripheral nerve to provide a source of neurons for muscle reinnervation, termed motoneuron integrated striated muscle (MISM), may provide the potential to restore functional muscle activity, when combined with computer-programmed functional electrical stimulation (FES).
Himanshu Arora et al.
Journal of stem cells & regenerative medicine, 17(1), 18-27 (2021-08-27)
Rationale: Cardiac sympathetic nerves are required for endogenous repair of the mammalian neonatal heart in vivo, but the underlying mechanism is unclear. Objective: We tested the hypothesis that a combination of cardiac developmental growth factors Wnt3a, BMP4 and Neuregulin (NRG-1)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门