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Merck
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主要文件

1.02497

Supelco

NMP

for headspace gas chromatography SupraSolv®

别名:

1-甲基-2-吡咯烷酮

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About This Item

CAS号:
分子量:
99.13
MDL编号:
UNSPSC代码:
41116105
EC索引号:
212-828-1
NACRES:
NA.03
价格与库存信息目前不能提供

产品名称

1-甲基-2-吡咯烷酮, for headspace gas chromatography SupraSolv®

蒸汽压

0.32 hPa ( 20 °C)

质量水平

产品线

SupraSolv®

方案

≥99.8% (GC)

表单

liquid

自燃温度

245 °C

效能

3598 mg/kg LD50, oral (Rat)
8000 mg/kg LD50, skin (Rabbit)

expl. lim.

1.3-9.5 % (v/v)

技术

GC-HS: suitable

pH值(酸碱度)

8.5-10.0 (20 °C, 100 g/L in H2O)

沸点

202 °C/1013 hPa

mp

-24 °C

转变温度

flash point 91 °C

溶解性

1000 g/L

密度

1.03 g/cm3 at 20 °C

储存温度

2-30°C

SMILES字符串

N1(CCCC1=O)C

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

一般描述

SupraSolv® 高纯度溶剂专门用于顶空-气相色谱(HS-GC),用于根据欧洲药典和美国药典分析原料药、赋形剂和药物产品中的残留溶剂(RS)。高纯度溶剂中RS的浓度根据 ICH(国际人用药品注册技术要求协调理事会)指导原则Q3C“杂质:残留溶剂指导原则”规定。

应用

ICH 1、2和3类分析物的灵敏检测和环境分析:

各种1类残留溶剂,依据ICH ≤ 1 μg/g
各种2类残留溶剂,依据ICH ≤ 10 μg/g
各种3类残留溶剂,依据ICH ≤ 50 μg/g

其他说明

探索各种实验室安全配件和设备,以安全处理溶剂,从一开始就提高您的安全水平。

法律信息

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation markHealth hazard

警示用语:

Danger

危险分类

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

闪点(°F)

195.8 °F - Pensky-Martens closed cup

闪点(°C)

91 °C - Pensky-Martens closed cup


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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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