07-1387
抗氧化-CaM激酶II(Met281/282)抗体
serum, from rabbit
别名:
CAMKK beta protein, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, Calcium/calmodulin-dependent protein kinase kinase beta, calcium/calmodulin-dependent protein kinase beta, calcium/calmodulin-dependent protein kinase kinase 2 beta, calcium/calmodulin-
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About This Item
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生物源
rabbit
品質等級
抗體表格
serum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
物種活性
mouse, rat, human
技術
immunocytochemistry: suitable
western blot: suitable
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CAMK2D(817)
一般說明
Ca2+/钙调蛋白依赖性激酶家族包括CaM激酶I至IV,磷酸化酶激酶和MLCK。在没有刺激的情况下,CaM激酶是无活性的。与Ca2+/钙调蛋白的结合诱导构象变化和激活。CaM激酶具有广泛的底物特异性,具有许多细胞功能。
特異性
基于与免疫原序列的100%同源性,预期在小鼠和大鼠中发生交叉反应。
当在Met281/282上氧化时,该抗体可识别CaM激酶II。
免疫原
包含并包括氧化的Met281/282的合成肽。
表位:氧化Met281/282
應用
一个独立的实验室验证了该抗体在用盐水,AngII或Iso处理的小鼠心脏切片中的免疫细胞化学中起作用(Erickson,J.R.,2008)。
经验证,该抗氧化CaM激酶II(Met281/282)抗体可用于WB,IC检测氧化CaM激酶II(Met281/282)。
品質
通过蛋白质印迹在未处理和经H2O2处理的小鼠心脏细胞裂解液中进行了评估。
蛋白质印迹分析: 该抗体的1:1,000稀释液用于检测小鼠心脏细胞裂解液中氧化的CaM激酶II。
蛋白质印迹分析: 该抗体的1:1,000稀释液用于检测小鼠心脏细胞裂解液中氧化的CaM激酶II。
標靶描述
60 kDa
聯結
替代:04-1079
儲存和穩定性
自收到之日起,在-20°C条件下可稳定保存1年。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。
处理建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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