ALD00508

Yu Fluorination Ligand

≥95%

• 别名: 2,5,6,8-tetramethyl-3,4-dihydro-2H-pyrano[2,3-b]quinoline
• 经验公式（希尔记法）: C₁₆H₁₉NO
• CAS号: 1771764-64-7
• 分子量: 241.33
• MDL编号: MFCD29059851
• UNSPSC代码: 41116155
• PubChem化学物质编号: 329772697
• NACRES: NA.22

属性

• 质量水平: 100
• 方案: ≥95%
• 表单: powder
• 反应适用性: reagent type: catalyst; reagent type: ligand; reaction type: C-H Activation
• SMILES字符串: CC1=C2C(OC(C)CC2)=NC3=C1C(C)=CC(C)=C3
• InChI: 1S/C16H19NO/c1-9-7-10(2)15-12(4)13-6-5-11(3)18-16(13)17-14(15)8-9/h7-8,11H,5-6H2,1-4H3
• InChI key: LOKRNFHHPZEJLL-UHFFFAOYSA-N

说明

一般描述

Yu Fluorination Ligand is widely employed for the chemoselective functionalization of sp²- and sp³ C-H bonds.

应用

The Yu Fluorination Ligand in tandem with Selectfluor(R) (Aldrich 439479) under palladium catalysis can promote direct fluorination of C(sp³)-H bonds stereoselectively. Yu and coworkers have displayed this on amino acid derivatives with directing group assistance from the Yu-Wasa Auxiliary (Aldrich 791806).

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable