936413

Fmoc-Val-Cit-OH

≥95%

• 别名: (S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-methylbutanamido)-5-ureidopentanoicacid, N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valyl-N⁵-(aminocarbonyl)-L-ornithine (ACI), L-Ornithine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N⁵-(aminocarbonyl)-, L-Ornithine, N⁵-(aminocarbonyl)-N²-[N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl]- (ZCI)
• 经验公式（希尔记法）: C₂₆H₃₂N₄O₆
• CAS号: 159858-21-6
• 分子量: 496.56
• MDL號碼: MFCD28139060
• 分類程式碼代碼: 12352209
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: powder or crystals
• 顏色: white to beige
• 儲存溫度: 2-8°C
• SMILES 字串: C(OC(N[C@H](C(N[C@@H](CCCNC(N)=O)C(O)=O)=O)C(C)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
• InChI: InChI=1S/C26H32N4O6/c1-15(2)22(23(31)29-21(24(32)33)12-7-13-28-25(27)34)30-26(35)36-14-20-18-10-5-3-8-16(18)17-9-4-6-11-19(17)20/h3-6,8-11,15,20-22H,7,12-14H2,1-2H3,(H,29,31)(H,30,35)(H,32,33)(H3,27,28,34)/t21-,22-/m0/s1
• InChI 密鑰: ZJLNQOIFTYLCHC-VXKWHMMOSA-N

说明

應用

This is a cathepsin cleavable linker used in bioconjugation, specifically in the construction of antibody drug conjugates (ADC & Bioconjugation).

特點和優勢

Fmoc-Val-Cit-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B.

其他說明

ADC & Bioconjugation

Chemical Biology Tools

http://pubs.rsc.org/en/Content/ArticleLanding/2011/MB/C0MB00074D#!divAbstract

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable