跳转至内容
Merck
所有图片(1)

文件

759902

Sigma-Aldrich

Dibenzocyclooctyne-PEG4-acid

for Copper-free Click Chemistry

别名:

Polyethylene glycol, DBCO-PEG4-Acid

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C32H40N2O8
分子量:
580.67
MDL號碼:
MFCD22380749
分類程式碼代碼:
12352106
PubChem物質ID:
329766822
NACRES:
NA.22

形狀

solid

反應適用性

reaction type: click chemistry
reagent type: linker

官能基

carboxylic acid

儲存溫度

−20°C

SMILES 字串

O=C(CCCCC(NCCOCCOCCOCCOCCC(O)=O)=O)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3

InChI

1S/C32H40N2O8/c35-30(33-16-18-40-20-22-42-24-23-41-21-19-39-17-15-32(37)38)11-5-6-12-31(36)34-25-28-9-2-1-7-26(28)13-14-27-8-3-4-10-29(27)34/h1-4,7-10H,5-6,11-12,15-25H2,(H,33,35)(H,37,38)

InChI 密鑰

RMYANOWYMFCGGS-UHFFFAOYSA-N

相关类别

應用

Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. The PEG spacer adds hydrophilicity to the product to decrease aggregation.
Dibenzocyclooctyne-PEG4-acid may be used as a substrate in azide-cyclooctyne cycloaddition reactions.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Jianwen Xu et al.
Chemistry, an Asian journal, 6(10), 2730-2737 (2011-09-29)
Strategies to encapsulate cells in cytocompatible three-dimensional hydrogels with tunable mechanical properties and degradability without harmful gelling conditions are highly desired for regenerative medicine applications. Here we reported a method for preparing poly(ethylene glycol)-co-polycarbonate hydrogels through copper-free, strain-promoted azide-alkyne cycloaddition
A Versatile Monomer for Preparing Well-Defined Functional Polycarbonates and Poly(estercarbonates)
Xu J.; et al.
Macromolecules, 44, 2260-2267 (2011)
Selvanathan Arumugam et al.
Bioorganic & medicinal chemistry letters, 21(23), 6987-6991 (2011-10-26)
N-Terminally azido-modified peptides were labeled with the novel prosthetic labeling synthon [(18)F]azadibenzocyclooctyne ([(18)F]ADIBO) using copper-free azide-alkyne [3+2]-dipolar cycloaddition in high radiochemical yields (RCYs). (18)F-Labeled [(18)F]ADIBO was prepared by nucleophilic substitution of the corresponding tosylate in 21% overall RCY (EOB) in
Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi?Target Imaging
Karver MR, et al.
Angewandte Chemie (International Edition in English), 51(4), 920-922 (2012)
Strain-promoted copper-free "click" chemistry for 18F radiolabeling of bombesin.
Lachlan S Campbell-Verduyn et al.
Angewandte Chemie (International ed. in English), 50(47), 11117-11120 (2011-10-01)
查看所有相关文献

商品

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Copper-Free Click Chemistry

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

无铜点击化学

无铜点击化学是点击化学的一种替代方法，可在较低的活化屏障下进行，且没有细胞毒性过渡金属催化剂。

查看所有结果

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门