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Merck

485926

Sigma-Aldrich

L-乳酸钠-13C3 溶液

45-55 % (w/w) in H2O, ≥99 atom % 13C, ≥98% (CP), ≥98% (Chiral purity, HPLC)

别名:

L-乳酸-13C3 钠盐 溶液

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About This Item

线性分子式:
13CH313CH(OH)13CO2Na
分子量:
115.04
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.12

描述

Packaged as gram of solution 45-55%(w/w)

同位素純度

≥99 atom % 13C

化驗

≥98% (CP)
≥98% (Chiral purity, HPLC)

濃度

45-55 % (w/w) in H2O

技術

mass spectrometry (MS): suitable

mp

163-165 °C (lit.)

質量偏移

M+3

儲存溫度

−20°C

SMILES 字串

[Na+].[13CH3][13C@H](O)[13C]([O-])=O

InChI

1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1/i1+1,2+1,3+1;

InChI 密鑰

NGSFWBMYFKHRBD-USULVYIHSA-M

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一般說明

L-乳酸钠13C3 是 L-乳酸钠的同位素类似物。

應用

L-乳酸-13C3钠盐已用作LC/MS技术定量分析鼠肿瘤组织间液代谢物的内标。
L-乳酸钠-13C3 可用作内标物,用于通过滤纸干燥的血斑和之后的LC-MS/MS法定量测定血液乳酸盐和丙酮酸盐。它还可用于研究NAD氧化还原代谢或乳酸盐水平,其有助于开发新的癌症免疫疗法和治疗性免疫抑制。

包裝

该产品可从散装库存中获得,并可根据需要进行包装。有关价格、可用性和包装的信息,请联系稳定同位素客户服务部门

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Jin-Wen Song et al.
Cell metabolism, 32(2), 188-202 (2020-07-02)
The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented threat to global public health. Herein, we utilized a combination of targeted and untargeted tandem mass spectrometry to analyze the plasma lipidome and metabolome in mild, moderate, and severe COVID-19 patients
Isolation and Quantification of Metabolite Levels in Murine Tumor Interstitial Fluid by LC/MS
Sullivan MR, et al.
Bio-protocol, 9, e3427-e3427 (2019)
M Testa et al.
Journal of ocular pharmacology, 3(3), 211-225 (1987-01-01)
Substances derived from biotransformation of non-steroid antiinflammatory drugs (NSAID) produced by patients responsive to the biological liquid oxidant activity (BLOA) test, have been shown to have anticataract activity. They are all aromatic alcohols with physico-chemical properties similar to benzyl alcohols
Chih-Kuang Chuang et al.
Journal of chromatography. A, 1216(51), 8947-8952 (2009-11-17)
Lactic acidemia is commonly associated with severe diseases in pediatric patients. Quantitation of blood lactate and pyruvate is important for the diagnosis and clinical management. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method using dried blood spots (DBS) was developed and
Minfeng Ying et al.
Redox biology, 46, 102065-102065 (2021-07-23)
Although glucose, through pentose phosphate pathway (PPP), is the main source to generate NADPH, solid tumors are often deprived of glucose, hence alternative metabolic pathways to maintain NADPH homeostasis in cancer cells are required. Here, we report that lactate and

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