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T2501

Sigma-Aldrich

L-Thyroxin Natriumsalz Pentahydrat

≥98% (HPLC), powder

Synonym(e):

3-[4-(4-Hydroxy-3,5-diiodphenoxy)-3,5-diiodphenyl]-L-alanin Natriumsalz, Natrium-levothyroxin, T4

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About This Item

Lineare Formel:
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
CAS-Nummer:
6106-07-6
Molekulargewicht:
888.93
Beilstein:
5721845
EG-Nummer:
200-221-4
MDL-Nummer:
MFCD00149110
UNSPSC-Code:
51111800
PubChem Substanz-ID:
24900041
NACRES:
NA.32

Biologische Quelle

synthetic (organic)

Qualitätsniveau

200

Sterilität

non-sterile

Assay

≥98% (HPLC)

Form

powder

mp (Schmelzpunkt)

207-210 (dec.) (lit.)

Löslichkeit

4 M NH4OH in methanol: 50 mg/mL, clear to hazy, colorless to yellow

Versandbedingung

ambient

Lagertemp.

−20°C

SMILES String

O.O.O.O.O.[Na+].N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C([O-])=O

InChI

1S/C15H11I4NO4.Na.5H2O/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;;;;;;/h1-2,4-5,12,21H,3,20H2,(H,22,23);;5*1H2/q;+1;;;;;/p-1/t12-;;;;;;/m0....../s1

InChIKey

JMHCCAYJTTWMCX-QWPJCUCISA-M

Angaben zum Gen

mouse ... Cnr2(12802)
rat ... Cnr1(25248)

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Verwandte Kategorien

Biochem./physiol. Wirkung

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Angaben zur Herstellung

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

Ähnliches Produkt

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H372

Gefahreneinstufungen

STOT RE 1

Zielorgane

Thyroid,Cardio-vascular system,Kidney

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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