T1157

(+)-α-Tocopherol acetate

BioReagent, suitable for insect cell culture, ~1360 IU/g

• Synonym(e): Vitamin E acetate
• Empirische Formel (Hill-System): C₃₁H₅₂O₃
• CAS-Nummer: 58-95-7
• Molekulargewicht: 472.74
• EG-Nummer: 200-405-4
• MDL-Nummer: MFCD00072052
• UNSPSC-Code: 12352205
• eCl@ss: 34058007
• PubChem Substanz-ID: 24899940
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: plant
• Qualitätsniveau: 200
• Beschreibung: Synthesized from natural α-tocopherol
• Produktlinie: BioReagent
• Form: liquid (or semi-solid)
• Spezifische Aktivität: ~1360 IU/g
• Mol-Gew.: M_w 472.74 g/mol
• Aufgereinigt durch: crystallization
• Methode(n): cell culture | insect: suitable
• Farbe: white to yellow
• Löslichkeit: chloroform: soluble 50 mg/mL, clear, colorless to yellow
• Lagertemp.: room temp
• SMILES String: CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1
• InChI: 1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
• InChIKey: ZAKOWWREFLAJOT-CEFNRUSXSA-N

Beschreibung

Allgemeine Beschreibung

α-Tocopherol acetate is a semisynthetic acetate ester of naturally occurring α-tocopherol.

Anwendung

(+)-α-Tocopherol acetate has been used:

• as a supplement in the human embryonic kidney cells (HEK 293) to assess its impact on cell growth
• as a component of Dulbecco′s Modified Eagle Medium/Nutrient Mixture F-12 (DMEM/F12) for immortalized chondrocyte cell line
• as a component of serum-free medium for human colon tissue organ culture
• to test its antioxidant effects on cow articular chondrocytes

Use in insect cell culture applications as an antioxidant.

Biochem./physiol. Wirkung

α-Tocopherol acetate or vitamin E-acetate has antioxidant properties and reduces lipid peroxidation. However, vitamin E acetate on pyrolysis leads to the generation of carcinogens like alkenes and benzenes.

Vorsicht

Since the M.P. is about 25 °C this preparation is usually an oil. Does not air oxidize.

Sicherheitshinweise

• H-Sätze: H413
• P-Sätze: P273 - P501
• Gefahreneinstufungen: Aquatic Chronic 4
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Persönliche Schutzausrüstung: Eyeshields, Gloves