SRP3271

GM-CSF rat

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• Synonym(e): CSF-3, GM-CSF?, MGI-1G, pluripoietin
• UNSPSC-Code: 12352202
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: rat
• Rekombinant: expressed in E. coli
• Assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Form: lyophilized
• Wirksamkeit: ≥0.01 ng/mL
• Mol-Gew.: 14.5 kDa
• Verpackung: pkg of 20 μg
• Verunreinigungen: <0.1 EU/μg endotoxin, tested
• Farbe: white to off-white
• UniProt-Hinterlegungsnummer: P01587
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: rat ... CSF2(12981)

Beschreibung

Allgemeine Beschreibung

It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity.

Biochem./physiol. Wirkung

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Recombinant murine GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.

Physikalische Form

Lyophilized from 10 mM Tris, pH 8.5

Rekonstituierung

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable