SML3779

Methotrexate disodium salt

≥98% (HPLC)

• Synonym(e): Amethopterin sodium, N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid disodium salt, Sodium methotrexate
• Empirische Formel (Hill-System): C₂₀H₂₀N₈Na₂O₅
• CAS-Nummer: 7413-34-5
• Molekulargewicht: 498.40
• MDL-Nummer: MFCD00274560
• UNSPSC-Code: 12352200
• NACRES: NA.21

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to brown
• Löslichkeit: H₂O: 2 mg/mL, clear
• Lagertemp.: -10 to -25°C
• SMILES String: [Na].[Na].N([C@@H](CCC(=O)O)C(=O)O)C(=O)c1ccc(cc1)N(Cc2nc3c(nc(nc3N)N)nc2)C
• InChIKey: HQRCOVOSZPGUCA-GXKRWWSZSA-N

Beschreibung

Biochem./physiol. Wirkung

Methotrexate disodium salt is a potent is a folic acid antagonist that is used as an antineoplastic and antirheumatic drug. Methotrexate disodium salt is a potent inhibitor of dihydrofolate reductase.

Vorsicht

Hygroscopic

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H315,H319,H341,H360D
• P-Sätze: P202 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Eye Irrit. 2 - Muta. 2 - Repr. 1B - Skin Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable