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Merck

N0786

Sigma-Aldrich

β-Nicotinamidadenin-Dinucleotid, reduziert Dinatriumsalz Hydrat

~98%, pkg of 1 mg (per vial)

Synonym(e):

Coenzym I red. Dinatriumsalz, DPNH2-Na2, Diphosphopyridinnucleotid reduziert Dinatriumsalz Hydrat, NADH Na2

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About This Item

Empirische Formel (Hill-System):
C21H27N7Na2O14P2
CAS-Nummer:
Molekulargewicht:
709.40
Beilstein:
5230241
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51

Assay

~98%

Qualitätsniveau

Form

powder

Verpackung

pkg of 1 mg (per vial)

Löslichkeit

10 mM NaOH: 0.1 mg/mL, clear, colorless

SMILES String

[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O

InChI

1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11+,13-,14+,15-,16+,20-,21+;;/m0../s1

InChIKey

QRGNQKGQENGQSE-QUWMEQBESA-L

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Anwendung

β-Nicotinamide adenine dinucleotide, reduced disodium salt has been used in the preparation of standard curve.

Biochem./physiol. Wirkung

β-Nicotinamide adenine dinucleotide (β-NADH) reduced form is an essential cofactor in all the living organisms. β-NADH functions as a hydride donor in biochemical redox reactions.
Electron donor

Rekonstituierung

Solutions should be prepared fresh and used promptly.

Sonstige Hinweise

Packaged based on NADH content as determined by UV-Vis.
This is the common form of NADH; do not confuse with α-NADH.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

The biosynthesis of nicotinamide adenine dinucleotides in bacteria
Begley TP, et al.
Vitamins and Hormones, 61, 103-119 (2001)
Milk composition and health status from mammary gland quarters adjacent to glands affected with naturally occurring clinical mastitis
Paixao MG, et al.
Journal of Dairy Science, 100(9), 7522-7533 (2017)
Michael O Hottiger
FEBS letters, 585(11), 1595-1599 (2011-03-23)
ADP-ribosylation is a covalent post-translational protein modification catalyzed by ADP-ribosyltransferases and is involved in important processes such as cell cycle regulation, DNA damage response, replication or transcription. Histones are ADP-ribosylated by ADP-ribosyltransferase diphtheria toxin-like 1 at specific amino acid residues
Andreas Grahnert et al.
Innate immunity, 17(2), 212-233 (2010-04-15)
Latterly, nicotinamide adenine dinucleotide (NAD+) has emerged as a molecule with versatile functions and of enormous impact on the maintenance of cell integrity. Besides playing key roles in almost all major aspects of energy metabolism, there is mounting evidence that
Richard P Ebstein et al.
FEBS letters, 585(11), 1529-1536 (2011-05-12)
Increasing evidence suggests that the nonapeptide, oxytocin (OT), helps shape social and affiliative behaviors not only in lower mammals but also in humans. Recently, an essential mediator of brain OT release has been discovered, ADP-ribosyl cyclase and/or CD38. We have

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