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MAK053

Sigma-Aldrich

Alcohol Dehydrogenase Activity Assay Kit

sufficient for 100 colorimetric tests

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About This Item

UNSPSC-Code:
12161503
NACRES:
NA.84

Verwendung

sufficient for 100 colorimetric tests

Nachweisverfahren

colorimetric

Relevante Krankheit(en)

gastrointestinal diseases

Lagertemp.

−20°C

Angaben zum Gen

human ... ADH1A(124) , ADH1B(125) , ADH1C(126) , ADH4(127) , ADH5(128) , ADH6(130) , ADH7(131)
mouse ... ADH1C(11522) , ADH4(26876) , ADH5(11532) , ADH6A(69117) , ADH7(11529)
rat ... ADH1C(24172) , ADH4(29646) , ADH5(100145871) , ADH6(310903) , ADH6A(295498) , ADH7(171178)

Allgemeine Beschreibung

The new Alcohol Dehydrogenase (ADH) Assay Kit, MAK498, is now available! Alcohol dehydrogenases (ADH) are a family of enzymes that catalyzes the conversion of alcohols to aldehydes, with the concomitant reduction of NAD+ to NADH. In humans, there are nine isozymes of ADH, with the majority of ADH activity occurring in the liver. ADH family members are the primary enzymes involved in alcohol detoxification. Genetic variations in ADH enzymes result in differences in ADH activity and tolerances for alcohol, and may regulate susceptibility to alcoholism.

Anwendung

Alcohol Dehydrogenase Activity Assay Kit has been used to determine the activity of alcohol dehydrogenase.

Eignung

Suitable for the detection of alcohol dehydrogenase in a variety of samples including tissue, cells and serum.

Prinzip

The Alcohol Dehydrogenase Activity Assay kit provides a simple and direct procedure for measuring ADH activity in a variety of samples. ADH activity is determined using ethanol as the substrate in an enzyme reaction, which results in a colorimetric (450 nm) product proportional to the enzymatic activity present. One unit of ADH is the amount of enzyme that will generate 1.0 μmole of NADH per minute at pH 8.0 at 37 °C.

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Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

FlameExclamation mark
GHS02,GHS07

Signalwort

Danger

Gefahreneinstufungen

Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

Flammpunkt (°F)

53.6 °F - closed cup

Flammpunkt (°C)

12.0 °C - closed cup

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Brain research, 1747, 147067-147067 (2020-08-23)
Research focusing on the gut-brain axis is growing, but the interplay of ethanol (alcohol molecule), the gut microbiome, the brain and behavior is poorly understood. In the current study, we remodeled the gut microbiota by providing adult male C57BL/6J mice
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Tian L, et al.
International Journal of Biological Sciences, 12(9), 1052-1052 (2016)
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Animal-microbe mutualisms are typically maintained by vertical symbiont transmission or partner choice. A third mechanism, screening of high-quality symbionts, has been predicted in theory, but empirical examples are rare. Here we demonstrate that ambrosia beetles rely on ethanol within host
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Scientific reports, 9(1), 6491-6491 (2019-04-26)
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